(Q88167003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

title

Phase Transitions in the Assembly and Function of Human miRISC (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0140364

author name string

Jessica Sheu-Gruttadauria

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

Ian J MacRae

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

publication date

22 March 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

volume

173

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

page(s)

946-957.e16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

21 March 2020

ImageQuant

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5935535/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles

1 reference

12 December 2020

Effect of polyethylene glycol on the liquid-liquid phase transition in aqueous protein solutions

1 reference

12 December 2020

The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies

1 reference

12 December 2020

RISC is a 5' phosphomonoester-producing RNA endonuclease

1 reference

12 December 2020

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

1 reference

12 December 2020

Argonaute2 is the catalytic engine of mammalian RNAi

1 reference

12 December 2020

GW182 is critical for the stability of GW bodies expressed during the cell cycle and cell proliferation

1 reference

12 December 2020

Two RNAi complexes, RITS and RDRC, physically interact and localize to noncoding centromeric RNAs.

1 reference

12 December 2020

RNA interference (RNAi)-dependent and RNAi-independent association of the Chp1 chromodomain protein with distinct heterochromatic loci in fission yeast.

1 reference

12 December 2020

MicroRNAs regulate brain morphogenesis in zebrafish

1 reference

12 December 2020

Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies

1 reference

12 December 2020

The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans

1 reference

12 December 2020

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

1 reference

12 December 2020

A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

1 reference

12 December 2020

Disruption of GW bodies impairs mammalian RNA interference

1 reference

12 December 2020

A role for the P-body component GW182 in microRNA function

1 reference

12 December 2020

Identification of novel argonaute-associated proteins

1 reference

12 December 2020

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

1 reference

12 December 2020

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

1 reference

12 December 2020

P-body formation is a consequence, not the cause, of RNA-mediated gene silencing

1 reference

12 December 2020

RNA-binding proteins: modular design for efficient function

1 reference

12 December 2020

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

1 reference

12 December 2020

Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

1 reference

12 December 2020

Dynamic regulation of ARGONAUTE4 within multiple nuclear bodies in Arabidopsis thaliana

1 reference

12 December 2020

Most mammalian mRNAs are conserved targets of microRNAs

1 reference

12 December 2020

An atypical RNA polymerase involved in RNA silencing shares small subunits with RNA polymerase II.

1 reference

12 December 2020

Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation

1 reference

12 December 2020

MicroRNAs: target recognition and regulatory functions

1 reference

12 December 2020

Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila

1 reference

12 December 2020

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

1 reference

12 December 2020

A C-terminal silencing domain in GW182 is essential for miRNA function

1 reference

12 December 2020

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

1 reference

12 December 2020

An effector of RNA-directed DNA methylation in arabidopsis is an ARGONAUTE 4- and RNA-binding protein.

1 reference

12 December 2020

Germline P granules are liquid droplets that localize by controlled dissolution/condensation

1 reference

12 December 2020

Functional dissection of the human TNRC6 (GW182-related) family of proteins

1 reference

12 December 2020

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps

1 reference

12 December 2020

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation

1 reference

12 December 2020

1 reference

12 December 2020

PHENIX: a comprehensive Python-based system for macromolecular structure solution

1 reference

12 December 2020

Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein

1 reference

12 December 2020

Coilin-dependent snRNP assembly is essential for zebrafish embryogenesis

1 reference

12 December 2020

Features and development of Coot

1 reference

12 December 2020

Mammalian microRNAs predominantly act to decrease target mRNA levels

1 reference

12 December 2020

Divergent GW182 functional domains in the regulation of translational silencing

1 reference

12 December 2020

Overview of the CCP4 suite and current developments

1 reference

12 December 2020

GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets

1 reference

12 December 2020

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs

1 reference

12 December 2020

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT

1 reference

12 December 2020

The microcosmos of cancer

1 reference

12 December 2020

Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish

1 reference

12 December 2020

miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay

1 reference

12 December 2020

The Crystal Structure of Human Argonaute2

1 reference

12 December 2020

The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex

1 reference

12 December 2020

MicroRNAs mediate gene silencing via multiple different pathways in drosophila

1 reference

12 December 2020

Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus

1 reference

12 December 2020

Rapid and specific purification of Argonaute-small RNA complexes from crude cell lysates

1 reference

12 December 2020

Highly complementary target RNAs promote release of guide RNAs from human Argonaute2

1 reference

12 December 2020

Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair

1 reference

12 December 2020

Structure of the PAN3 pseudokinase reveals the basis for interactions with the PAN2 deadenylase and the GW182 proteins

1 reference

12 December 2020

Structural features of Argonaute-GW182 protein interactions

1 reference

12 December 2020

Structure and assembly of the NOT module of the human CCR4-NOT complex

1 reference

12 December 2020

Phase transitions and size scaling of membrane-less organelles

1 reference

12 December 2020

Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression

1 reference

12 December 2020

A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing

1 reference

12 December 2020

An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration

1 reference

12 December 2020

In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

1 reference

12 December 2020

Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation

1 reference

12 December 2020

An asymmetric PAN3 dimer recruits a single PAN2 exonuclease to mediate mRNA deadenylation and decay

1 reference

12 December 2020

The structure of the Pan2-Pan3 core complex reveals cross-talk between deadenylase and pseudokinase

1 reference

12 December 2020

Structural basis for microRNA targeting

1 reference

12 December 2020

Towards a molecular understanding of microRNA-mediated gene silencing

1 reference

12 December 2020

Predicting effective microRNA target sites in mammalian mRNAs

1 reference

12 December 2020

RNA transcription modulates phase transition-driven nuclear body assembly

1 reference

12 December 2020

Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization

1 reference

12 December 2020

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

1 reference

12 December 2020

A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome

1 reference

12 December 2020

Emerging Roles of Disordered Sequences in RNA-Binding Proteins

1 reference

12 December 2020

Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm

1 reference

12 December 2020

miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning

1 reference

12 December 2020

Coexisting Liquid Phases Underlie Nucleolar Subcompartments

1 reference

12 December 2020

GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis

1 reference

12 December 2020

Reentrant Phase Transition Drives Dynamic Substructure Formation in Ribonucleoprotein Droplets.

1 reference

12 December 2020

Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins.

1 reference

12 December 2020

Splicing Activation by Rbfox Requires Self-Aggregation through Its Tyrosine-Rich Domain

1 reference

12 December 2020

Multivalent Recruitment of Human Argonaute by GW182.

1 reference

12 December 2020

Numerous interactions act redundantly to assemble a tunable size of P bodies in Saccharomyces cerevisiae

1 reference

12 December 2020

10.1016/J.CELL.2018.02.051

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29576456%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

1 reference