(Q88643680)

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(-)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer

scientific article published on 11 May 2018

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

(-)-Epigallocatechin 3-Gallate Synthetic Analogues Inhibit Fatty Acid Synthase and Show Anticancer Activity in Triple Negative Breast Cancer (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Sònia Palomeras

2

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26 March 2020

3

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Europe PubMed Central

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26 March 2020

Marta Planas Grabuleda

6

1 reference

Europe PubMed Central

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26 March 2020

7

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Europe PubMed Central

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26 March 2020

author name string

Joan Crous-Masó

1

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26 March 2020

Cristina Camó

4

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26 March 2020

Úrsula Martínez-Garza

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

Teresa Puig

8

1 reference

Europe PubMed Central

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26 March 2020

publication date

11 May 2018

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Europe PubMed Central

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26 March 2020

1 reference

Europe PubMed Central

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26 March 2020

23

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26 March 2020

5

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Europe PubMed Central

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26 March 2020

copyright license

Creative Commons Attribution 4.0 International

11 May 2018

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April 2022 Public Data File from Crossref

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6099607/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Regulation of fatty acid synthase expression in breast cancer by sterol regulatory element binding protein-1c

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tamoxifen and epigallocatechin gallate are synergistically cytotoxic to MDA-MB-231 human breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

mTOR signaling: implications for cancer and anticancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The crystal structure of a mammalian fatty acid synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between fatty acid synthase- and ErbB-systems in ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hallmarks of Cancer: The Next Generation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavonoids: potential Wnt/beta-catenin signaling modulators in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New synthetic inhibitors of fatty acid synthase with anticancer activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer treatment and survivorship statistics, 2014

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular Pathways: Fatty Acid Synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Emerging Hallmarks of Cancer Metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of Clinicopathological Features and Prognosis in Triple-Negative and Non-Triple Negative Breast Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple-Negative Breast Cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-negative breast cancer: is there a treatment on the horizon?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular alterations in triple-negative breast cancer-the road to new treatment strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigallocatechin gallate inhibits the growth of MDA-MB-231 breast cancer cells via inactivation of the β-catenin signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid synthase expression and its association with clinico-histopathological features in triple-negative breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29751678

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES23051160

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29751678%20AND%20SRC:MED&resulttype=core&format=json

26 March 2020

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