(Q89093510)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

NEDD9 targets COL3A1 to promote endothelial fibrosis and pulmonary arterial hypertension (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

main subject

arterial hypertension

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Lai-Ming Yung

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Marcel Brown

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Frederick P Bowman

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

William M Oldham

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Brian B Graham

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Sachiko Seo

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Vadim N. Gladyshev

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Paul B Yu

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Laura E Fredenburgh

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Bradley A Maron

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

author name string

Thomas Stephens

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Bradley M Wertheim

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Rui-Sheng Wang

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Sara O Vargas

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Minwei Cao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Elena Arons

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Paul B Dieffenbach

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Jason G Fewell

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Majed Matar

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Kathleen J Haley

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

George A Alba

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Stefano M Marino

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Rahul Kumar

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Ivan O Rosas

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Aaron B Waxman

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Dinesh Khanna

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Joseph Loscalzo

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Jane A Leopold

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

publication date

1 June 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

Science Translational Medicine

31 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

445

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

31 March 2020

Cytoscape

1 reference

9 June 2022

https://europepmc.org/search?query=(METHODS:'Cytoscape')

inferred from PubMed Central ID database lookup

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Human enhancer of filamentation 1, a novel p130cas-like docking protein, associates with focal adhesion kinase and induces pseudohyphal growth in Saccharomyces cerevisiae

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Regulation of collagen type I in vascular smooth muscle cells by competition between Nkx2.5 and deltaEF1/ZEB1

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Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis

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12 December 2020

Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance

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Direct observation of individual endogenous protein complexes in situ by proximity ligation

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12 December 2020

Aldosterone impairs vascular reactivity by decreasing glucose-6-phosphate dehydrogenase activity

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12 December 2020

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12 December 2020

LKB1 modulates lung cancer differentiation and metastasis

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12 December 2020

Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice

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12 December 2020

Interleukin-6 overexpression induces pulmonary hypertension

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12 December 2020

Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells

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12 December 2020

Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin

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12 December 2020

A redox switch in angiotensinogen modulates angiotensin release

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12 December 2020

Transcriptome analysis of aldosterone-regulated genes in human vascular endothelial cell lines stably expressing mineralocorticoid receptor

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12 December 2020

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function

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12 December 2020

PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9

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12 December 2020

Bisoprolol Delays Progression Towards Right Heart Failure in Experimental Pulmonary Hypertension

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12 December 2020

Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension

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12 December 2020

Subcellular localization of oxidants and redox modulation of endothelial nitric oxide synthase

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12 December 2020

Src binds cortactin through an SH2 domain cystine-mediated linkage.

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12 December 2020

Plasma aldosterone levels are elevated in patients with pulmonary arterial hypertension in the absence of left ventricular heart failure: a pilot study

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12 December 2020

Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension

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12 December 2020

Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension.

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12 December 2020

Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.

1 reference

12 December 2020

Transforming growth factor-β(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3

1 reference

12 December 2020

Transforming growth factor-β signaling promotes pulmonary hypertension caused by Schistosoma mansoni

1 reference

12 December 2020

Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

1 reference

12 December 2020

Relevant issues in the pathology and pathobiology of pulmonary hypertension

1 reference

12 December 2020

SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information

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12 December 2020

Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta.

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12 December 2020

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension

1 reference

12 December 2020

Upregulation of steroidogenic acute regulatory protein by hypoxia stimulates aldosterone synthesis in pulmonary artery endothelial cells to promote pulmonary vascular fibrosis

1 reference

12 December 2020

Src kinase determines the dynamic exchange of the docking protein NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesions.

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12 December 2020

Lipoic acid plays a role in scleroderma: insights obtained from scleroderma dermal fibroblasts

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12 December 2020

Endothelial-to-mesenchymal transition in pulmonary hypertension.

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12 December 2020

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12 December 2020

The role of Cas-L/NEDD9 as a regulator of collagen-induced arthritis in a murine model.

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12 December 2020

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

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12 December 2020

Cy-preds: An algorithm and a web service for the analysis and prediction of cysteine reactivity.

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12 December 2020

The effects of transfection reagent polyethyleneimine (PEI) and non-targeting control siRNAs on global gene expression in human aortic smooth muscle cells

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12 December 2020

Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension

1 reference

12 December 2020

Exosomes induce and reverse monocrotaline-induced pulmonary hypertension in mice

1 reference

12 December 2020

PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.

1 reference

12 December 2020

Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension

1 reference

12 December 2020

In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug

1 reference

12 December 2020

A Selective Transforming Growth Factor-β Ligand Trap Attenuates Pulmonary Hypertension

1 reference

12 December 2020

Identification of Nedd9 as a TGF-β-Smad2/3 Target Gene Involved in RANKL-Induced Osteoclastogenesis by Comprehensive Analysis.

1 reference

12 December 2020

Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertension

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12 December 2020

Inhibition of histone deacetylase reduces transcription of NADPH oxidases and ROS production and ameliorates pulmonary arterial hypertension

1 reference

12 December 2020

Diagnosis, Treatment, and Clinical Management of Pulmonary Arterial Hypertension in the Contemporary Era: A Review

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12 December 2020

Responses to reductive stress in the cardiovascular system

1 reference

12 December 2020

Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications

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12 December 2020

Aortopathy in a Mouse Model of Marfan Syndrome Is Not Mediated by Altered Transforming Growth Factor β Signaling

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12 December 2020

TGF-β activation by bone marrow-derived thrombospondin-1 causes Schistosoma- and hypoxia-induced pulmonary hypertension.

1 reference

12 December 2020

Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways

1 reference

12 December 2020

10.1126/SCITRANSLMED.AAP7294

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29899023%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference