(Q90634214)

English

miR-98 reduces endothelial dysfunction by protecting blood-brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model

scientific article published on 10 October 2019

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601141%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

miR-98 reduces endothelial dysfunction by protecting blood-brain barrier (BBB) and improves neurological outcomes in mouse ischemia/reperfusion stroke model (English)

1 reference

Europe PubMed Central

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15 April 2020

blood–brain barrier

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author name string

David L Bernstein

1

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15 April 2020

Viviana Zuluaga-Ramirez

2

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15 April 2020

Sachin Gajghate

3

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15 April 2020

Nancy L Reichenbach

4

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15 April 2020

Boris Polyak

5

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15 April 2020

Yuri Persidsky

6

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15 April 2020

Slava Rom

7

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15 April 2020

publication date

10 October 2019

1 reference

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15 April 2020

Journal of Cerebral Blood Flow & Metabolism

1 reference

Europe PubMed Central

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15 April 2020

271678X19882264

1 reference

Europe PubMed Central

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15 April 2020

Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cognitive and behavioral assessment in experimental stroke research: will it prove useful?

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monocyte chemoattractant protein-1 regulation of blood-brain barrier permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxious and hyperactive phenotype following brief ischemic episodes in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the chemokine CCL2 on blood-brain barrier permeability during ischemia-reperfusion injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cannabinoid CB(2) receptor activation decreases cerebral infarction in a mouse focal ischemia/reperfusion model

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effectiveness of siRNA uptake in target tissues by various delivery methods

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokines in vascular dysfunction and remodeling.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glycogen synthase kinase 3beta (GSK3beta) decreases inflammatory responses in brain endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular insights and therapeutic targets for blood-brain barrier disruption in ischemic stroke: critical role of matrix metalloproteinases and tissue-type plasminogen activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pericytes regulate the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling stroke in mice - middle cerebral artery occlusion with the filament model

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The proteome of mouse brain microvessel membranes and basal lamina

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine signaling modulates blood-brain barrier function

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pericytes: developmental, physiological, and pathological perspectives, problems, and promises

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation by glycogen synthase kinase-3 of inflammation and T cells in CNS diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycogen synthase kinase 3β inhibition prevents monocyte migration across brain endothelial cells via Rac1-GTPase suppression and down-regulation of active integrin conformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel in vivo siRNA delivery system specifically targeting liver cells for protection of ConA-induced fulminant hepatitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence, predictors, and outcomes of perioperative stroke in noncarotid major vascular surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and analysis of brain-sequestered leukocytes from Plasmodium berghei ANKA-infected mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective activation of cannabinoid receptor 2 in leukocytes suppresses their engagement of the brain endothelium and protects the blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

β2 integrin-mediated crawling on endothelial ICAM-1 and ICAM-2 is a prerequisite for transcellular neutrophil diapedesis across the inflamed blood-brain barrier

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protection after stroke: cellular effectors of neurovascular unit integrity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innovative thrombolytic strategy using a heterodimer diabody against TAFI and PAI-1 in mouse models of thrombosis and stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A selective cannabinoid CB2 agonist attenuates damage and improves memory retention following stroke in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-98 and let-7g* protect the blood-brain barrier under neuroinflammatory conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MicroRNA-Let-7a regulates the function of microglia in inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-98 protects endothelial cells against hypoxia/reoxygenation induced-apoptosis by targeting caspase-3.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mouse model of thromboembolic stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perioperative stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune cell trafficking across the barriers of the central nervous system in multiple sclerosis and stroke

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of miRNA expression across human tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of a mouse cerebral microvascular endothelial cell line (bEnd.3) after oxygen glucose deprivation and reoxygenation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of CNS-infiltrating and Resident Microglial Cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spatio-temporal profile, phenotypic diversity, and fate of recruited monocytes into the post-ischemic brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sevoflurane downregulates IGF‑1 via microRNA‑98.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Infiltration and persistence of lymphocytes during late-stage cerebral ischemia in middle cerebral artery occlusion and photothrombotic stroke models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perioperative stroke: pathophysiology and management.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglycemia-Driven Neuroinflammation Compromises BBB Leading to Memory Loss in Both Diabetes Mellitus (DM) Type 1 and Type 2 Mouse Models

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased BBB Permeability Enhances Activation of Microglia and Exacerbates Loss of Dendritic Spines After Transient Global Cerebral Ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In Vitro Blood-Brain Barrier Modeling adapted for Peripheral Blood Mononuclear Cell Transmigration from HIV-Positive Patients for Clinical Research on Therapeutic Drug Intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation and blood-brain barrier disruption following traumatic brain injury: Pathophysiology and potential therapeutic targets

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune Cells After Ischemic Stroke Onset: Roles, Migration, and Target Intervention

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cerebral endothelial cell as a key regulator of inflammatory processes in sterile inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of blood brain barrier permeability and tissue microstructure following controlled cortical impact injury in rat: A dynamic contrast-enhanced magnetic resonance imaging and diffusion kurtosis imaging study

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Current progress in searching for clinically useful biomarkers of blood-brain barrier damage following cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aspirin ameliorates lung cancer by targeting the miR-98/WNT1 axis

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/31601141

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1177/0271678X19882264

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601141%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31601141%20AND%20SRC:MED&resulttype=core&format=json

15 April 2020

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