(Q93921953)

English

Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

Utility of hepatocytes to model species differences in the metabolism of loxtidine and to predict pharmacokinetic parameters in rat, dog and man (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

1 reference

ChEBI release 2020-05-28

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

M K Bayliss

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

J A Bell

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

W N Jenner

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

G R Park

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

K Wilson

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

publication date

1 March 1999

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

29

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

253-268

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

7-Ethoxycoumarin O-deethylase kinetics in isolated rat, dog and human hepatocyte suspensions

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Histamine H2-Antagonists-Past, Present and Future

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Incorporation of in vitro drug metabolism data into physiologically-based pharmacokinetic models

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Studies on the biotransformation of lonazolac, bromerguride, lisuride and terguride in laboratory animals and their hepatocytes

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Isolated rat hepatocytes as a model to study drug metabolism: Dose-dependent metabolism of diphenylhydantoin

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Metabolism of minaprine in human and animal hepatocytes and liver microsomes—prediction of metabolismin vivo

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Species differences in metabolism of ketotifen in rat, rabbit and man: demonstration of similar pathways in vivo and in cultured hepatocytes.

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Correlation of drug conjugative metabolism rates between in vivo and in vitro: glucuronidation and sulfation of p-nitrophenol as a model compound in rat

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Clinical significance of pharmacokinetic models of hepatic elimination

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Primary cultures of adult rat hepatocytes--a model for the toxicity of histamine H2-receptor antagonists

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Prediction of the pharmacokinetic parameters of reduced-dolasetron in man using in vitro-in vivo and interspecies allometric scaling.

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Comparative drug metabolism of diazepam in hepatocytes isolated from man, rat, monkey and dog.

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Kinetics of diazepam metabolism in rat hepatic microsomes and hepatocytes and their use in predicting in vivo hepatic clearance.

1 reference

https://api.crossref.org/works/10.1080%2F004982599238650

21 January 2018

Identifiers

10.1080/004982599238650

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10219966%20AND%20SRC:MED&resulttype=core&format=json

11 May 2020

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