(Q95827751)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

title

Allelic variation in GAD1 (GAD67) is associated with schizophrenia and influences cortical function and gene expression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

1 reference

R E Straub

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

B K Lipska

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

M F Egan

3

1 reference

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30 May 2020

T E Goldberg

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

J H Callicott

5

1 reference

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30 May 2020

M B Mayhew

6

1 reference

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30 May 2020

R K Vakkalanka

7

1 reference

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30 May 2020

B S Kolachana

8

1 reference

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30 May 2020

J E Kleinman

9

1 reference

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30 May 2020

D R Weinberger

10

1 reference

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30 May 2020

publication date

1 May 2007

1 reference

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30 May 2020

1 reference

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30 May 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

issue

9

1 reference

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30 May 2020

page(s)

854-869

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

The future of genetic studies of complex human diseases

30 May 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The maddening hunt for madness genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The molecular genetics of schizophrenia: new findings promise new insights

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genome scan meta-analysis of schizophrenia and bipolar disorder, part II: Schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

An update on the genetics of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Schizophrenia genes - famine to feast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Disruption of two novel genes by a translocation co-segregating with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genetic variation in the 6p22.3 gene DTNBP1, the human ortholog of the mouse dysbindin gene, is associated with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Neuregulin 1 and susceptibility to schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Polymorphisms in the 13q33.2 gene G72/G30 are associated with childhood-onset schizophrenia and psychosis not otherwise specified

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Association and linkage analyses of RGS4 polymorphisms in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Support for RGS4 as a susceptibility gene for schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Metabotropic glutamate receptor 3 (GRM3) gene variation is not associated with schizophrenia or bipolar affective disorder in the German population

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Convergent evidence for impaired AKT1-GSK3beta signaling in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The emerging role of glutamate in the pathophysiology and treatment of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The discovery of susceptibility genes for mental disorders

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genes for schizophrenia? Recent findings and their pathophysiological implications

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Bringing order to the glutamate chaos in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GABAergic local circuit neurons and prefrontal cortical dysfunction in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GABAergic interneurons: implications for understanding schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GAD(67): the link between the GABA-deficit hypothesis and the dopaminergic- and glutamatergic theories of psychosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GABA and Schizophrenia: A Review of Basic Science and Clinical Studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Short- and long-range attraction of cortical GABAergic interneurons by neuregulin-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Evidence that interaction between neuregulin 1 and its receptor erbB4 increases susceptibility to schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Seizures and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Evidence for impaired cortical inhibition in schizophrenia using transcranial magnetic stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Abnormal functional lateralization of the sensorimotor cortex in patients with schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Cortical inhibitory neurons and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Decreased glutamic acid decarboxylase67 messenger RNA expression in a subset of prefrontal cortical gamma-aminobutyric acid neurons in subjects with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Density of glutamic acid decarboxylase 67 messenger RNA-containing neurons that express the N-methyl-D-aspartate receptor subunit NR2A in the anterior cingulate cortex in schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Neurochemical markers for schizophrenia, bipolar disorder, and major depression in postmortem brains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The hydrophilic isoform of glutamate decarboxylase, GAD67, is targeted to membranes and nerve terminals independent of dimerization with the hydrophobic membrane-anchored isoform, GAD65.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The level of GAD67 protein is highly sensitive to small increases in intraneuronal gamma-aminobutyric acid levels.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Effects of increased gamma-aminobutyric acid levels on GAD67 protein and mRNA levels in rat cerebral cortex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Rapid regulation of GAD67 mRNA and protein level in cortical neurons after sensory learning.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Learning-induced plasticity of cortical representations does not affect GAD65 mRNA expression and immunolabeling of cortical neuropil.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Trophic actions of GABA on neuronal development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Dynamic remodeling of dendritic arbors in GABAergic interneurons of adult visual cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GABAergic excitation promotes neuronal differentiation in adult hippocampal progenitor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GABA regulates synaptic integration of newly generated neurons in the adult brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Polymorphisms in glutamate decarboxylase genes: analysis in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GAD1 (2q31.1), which encodes glutamic acid decarboxylase (GAD67), is associated with childhood-onset schizophrenia and cortical gray matter volume loss

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Prefrontal neurons and the genetics of schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genes, dopamine and cortical signal-to-noise ratio in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

How many diseases does it take to map a gene with SNPs?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Relative risk of attention deficits in siblings of patients with schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genome-wide search for schizophrenia susceptibility loci: The NIMH genetics initiative and millennium consortium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Genome scan of European-American schizophrenia pedigrees: Results of the NIMH genetics initiative and millennium consortium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

NIMH Genetics Initiative Millenium Schizophrenia Consortium: linkage analysis of African-American pedigrees

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A potential vulnerability locus for schizophrenia on chromosome 6p24-22: evidence for genetic heterogeneity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Relative risk for cognitive impairments in siblings of patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Executive subprocesses in working memory: relationship to catechol-O-methyltransferase Val158Met genotype and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Serotonin transporter genetic variation and the response of the human amygdala

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Functional magnetic resonance imaging brain mapping in psychiatry: methodological issues illustrated in a study of working memory in schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

An expanded role for functional neuroimaging in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Single nucleotide polymorphism detection: allelic discrimination using TaqMan

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Transmission/disequilibrium tests for extended marker haplotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A generalization of the transmission/disequilibrium test for uncertain-haplotype transmission

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Merlin--rapid analysis of dense genetic maps using sparse gene flow trees

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

GOLD--graphical overview of linkage disequilibrium

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Unbiased application of the transmission/disequilibrium test to multilocus haplotypes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A New Statistical Method for Haplotype Reconstruction from Population Data

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A general test of association for quantitative traits in nuclear families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Critical factors in gene expression in postmortem human brain: Focus on studies in schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Structural and functional characterization of mouse glutamate decarboxylase 67 gene promoter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Sex differences in GABA turnover and glutamic acid decarboxylase (GAD(65) and GAD(67)) mRNA in the rat hypothalamus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Modulation of the truncated GAD25 by estrogen in the olfactory bulb of adult rats

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

A highly significant association between a COMT haplotype and schizophrenia.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Catechol O -methyltransferase val 158 -met genotype and individual variation in the brain response to amphetamine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

New evidence of association between COMT gene and prefrontal neurocognitive function in healthy individuals from sibling pairs discordant for psychosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

An Icelandic example of the impact of population structure on association studies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Extreme population differences across Neuregulin 1 gene, with implications for association studies.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

The genetics of sensory gating deficits in schizophrenia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001988

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001988

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17767149%20AND%20SRC:MED&resulttype=core&format=json

30 May 2020

1 reference