(Q96960161)

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Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in Lyme arthritis

scientific article published on 02 July 2020

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32613944%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

Human Fcγ-receptor IIb modulates pathogen-specific versus self-reactive antibody responses in Lyme arthritis (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32613944%20AND%20SRC:MED&resulttype=core&format=json

4 July 2020

1 reference

based on heuristic

inferred from title

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4 July 2020

Falk Nimmerjahn

10

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4 July 2020

author name string

Heike Danzer

1

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4 July 2020

Joachim Glaesner

2

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4 July 2020

Anne Baerenwaldt

3

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4 July 2020

Carmen Reitinger

4

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4 July 2020

Anja Lux

5

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4 July 2020

Lukas Heger

6

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4 July 2020

Diane Dudziak

7

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4 July 2020

Thomas Harrer

8

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4 July 2020

publication date

2 July 2020

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4 July 2020

1 reference

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4 July 2020

9

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4 July 2020

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1 reference

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A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. I. Regulatory FCGR2B polymorphisms and their association with systemic lupus erythematosus

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FcgammaRIIB as a modulator of autoimmune disease susceptibility

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Mechanisms of Autoantibody-Induced Pathology.

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Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice

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T Cells Exacerbate Lyme Borreliosis in TLR2-Deficient Mice

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Fc gamma receptor IIB on dendritic cells enforces peripheral tolerance by inhibiting effector T cell responses

1 reference

13 October 2023

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Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis

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FcgammaRIV: a novel FcR with distinct IgG subclass specificity

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The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis

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FcγRIIb controls bone marrow plasma cell persistence and apoptosis

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Lyme borreliosis in selected strains and ages of laboratory mice

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Fcγ receptor IIB (FcγRIIB) maintains humoral tolerance in the human immune system in vivo

1 reference

13 October 2023

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Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy

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13 October 2023

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Of mice and men: the need for humanized mouse models to study human IgG activity in vivo

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13 October 2023

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From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

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The important and diverse roles of antibodies in the host response to Borrelia infections.

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13 October 2023

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Expression profile of FcgammaRIIb on leukocytes and its dysregulation in systemic lupus erythematosus

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The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility

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13 October 2023

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The same tyrosine-based inhibition motif, in the intra-cytoplasmic domain of FcγRIIB, regulates negatively BCR-, TCR-, and FcR-dependent cell activation

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A Humanized Mouse Identifies the Bone Marrow as a Niche with Low Therapeutic IgG Activity

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Inhibitory Fcγ receptor is required for the maintenance of tolerance through distinct mechanisms

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FcgammaRIIB in autoimmunity and infection: evolutionary and therapeutic implications.

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Fcgamma receptors as regulators of immune responses

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Selective blockade of inhibitory Fcgamma receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells

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Systemic lupus erythematosus-associated defects in the inhibitory receptor FcgammaRIIb reduce susceptibility to malaria.

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Autoimmune Arthritides, Rheumatoid Arthritis, Psoriatic Arthritis, or Peripheral Spondyloarthritis Following Lyme Disease.

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Analysis of a wild mouse promoter variant reveals a novel role for FcγRIIb in the control of the germinal center and autoimmunity.

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FcgammaRIIB Ile232Thr transmembrane polymorphism associated with human systemic lupus erythematosus decreases affinity to lipid rafts and attenuates inhibitory effects on B cell receptor signaling.

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A promoter haplotype of the immunoreceptor tyrosine-based inhibitory motif-bearing FcgammaRIIb alters receptor expression and associates with autoimmunity. II. Differential binding of GATA4 and Yin-Yang1 transcription factors and correlated receptor

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