(Q141591)

Protein kinase-like domain superfamily

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily

1 reference

Armadillo-type fold

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain, protein family

1 reference

PIK-related kinase, FAT family

1 reference

PIK-related kinase family

1 reference

FATC domain, protein family

1 reference

Telomere-length maintenance and DNA damage repair, protein family

1 reference

Phosphatidylinositol 3/4-kinase, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

image

ATM 00000.png
2,100 × 2,100; 4.18 MB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

9 May 2019

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein kinase activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

DNA-dependent protein kinase activity

1 reference

9 May 2019

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein dimerization activity

1 reference

9 May 2019

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein N-terminus binding

1 reference

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1-phosphatidylinositol-3-kinase activity

1 reference

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein serine/threonine kinase activity

7 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

USP10 regulates p53 localization and stability by deubiquitinating p53

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

24 references

9 May 2019

ATM activation by ionizing radiation requires BRCA1-associated BAAT1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Functional interaction of BRCA1/ATM-associated BAAT1 with the DNA-PK catalytic subunit

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

A role for DEAD box 1 at DNA double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

MDC1 is a mediator of the mammalian DNA damage checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATM activation by ionizing radiation requires BRCA1-associated BAAT1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Interaction between ATM protein and c-Abl in response to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Tel2 regulates the stability of PI3K-related protein kinases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Systematic identification of molecular links between core and candidate genes in breast cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

The DNA damage sensors ataxia-telangiectasia mutated kinase and checkpoint kinase 2 are required for hepatitis C virus RNA replication

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Notch is a direct negative regulator of the DNA-damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATMIN defines an NBS1-independent pathway of ATM signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein-containing complex binding

1 reference

9 May 2019

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein serine/threonine kinase activity

9 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

USP10 regulates p53 localization and stability by deubiquitinating p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

The histone demethylase LSD1/KDM1A promotes the DNA damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

response to ionizing radiation

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

neuron apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

reciprocal meiotic recombination

1 reference

9 May 2019

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

female gamete generation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

determination of adult lifespan

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

establishment of protein-containing complex localization to telomere

1 reference

9 May 2019

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

meiotic telomere clustering

IC

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

peptidyl-serine autophosphorylation

1 reference

9 May 2019

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

DNA damage checkpoint signaling

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

regulation of telomerase activity

1 reference

9 May 2019

ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of telomerase catalytic core complex assembly

1 reference

9 May 2019

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of neuron death

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

mitotic spindle assembly checkpoint signaling

1 reference

9 May 2019

Involvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

lipoprotein catabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of cell cycle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

protein phosphorylation

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of neuron apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

negative regulation of telomere capping

1 reference

9 May 2019

MRE11-RAD50-NBS1 and ATM function as co-mediators of TRF1 in telomere length control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of apoptotic process

1 reference

9 May 2019

ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of cellular response to heat

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

histone mRNA catabolic process

1 reference

9 May 2019

Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

cellular response to nitrosative stress

1 reference

9 May 2019

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of DNA damage response, signal transduction by p53 class mediator

1 reference

9 May 2019

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

double-strand break repair via nonhomologous end joining

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

negative regulation of B cell proliferation

1 reference

9 May 2019

ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

A single ataxia telangiectasia gene with a product similar to PI-3 kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

establishment of RNA localization to telomere

1 reference

9 May 2019

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

DNA double-strand break processing

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of signal transduction by p53 class mediator

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

phosphatidylinositol-3-phosphate biosynthetic process

1 reference

9 May 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

cellular response to X-ray

1 reference

9 May 2019

NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

double-strand break repair via homologous recombination

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

ovarian follicle development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

immune system process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

immunoglobulin production

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

male meiotic nuclear division

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

female meiotic nuclear division

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

female gonad development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

post-embryonic development

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

multicellular organism growth

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

protein autophosphorylation

3 references

9 May 2019

Molecular and Functional Characterization of a Cohort of Spanish Patients with Ataxia-Telangiectasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

chromosome organization involved in meiotic cell cycle

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

cellular response to DNA damage stimulus

6 references

16 July 2018

ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

16 July 2018

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

regulation of telomere maintenance via telomerase

1 reference

9 May 2019

ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of DNA catabolic process

IGI

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of microglial cell activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

regulation of cellular response to gamma radiation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of response to DNA damage stimulus

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

pre-B cell allelic exclusion

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

regulation of autophagy

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of telomere maintenance via telomerase

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

negative regulation of TORC1 signaling

1 reference

16 July 2018

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13315&geneProductId=UniProtKB:Q13315

DNA damage checkpoint signaling

cellular response to DNA damage stimulus

7 references

9 May 2019

ATM, CTLA4, MNDA, and HEM1 in high versus low CD38 expressing B-cell chronic lymphocytic leukemia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

PARP1-dependent recruitment of KDM4D histone demethylase to DNA damage sites promotes double-strand break repair

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin

Critical Assessment of Protein Function Annotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

intrinsic apoptotic signaling pathway in response to DNA damage

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of gene expression

1 reference

9 May 2019

The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of cell migration

1 reference

9 May 2019

The over expression of long non-coding RNA ANRIL promotes epithelial-mesenchymal transition by activating the ATM-E2F1 signaling pathway in pancreatic cancer: An in vivo and in vitro study.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of cell adhesion

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

positive regulation of transcription by RNA polymerase II

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

cellular response to retinoic acid

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a)

replicative senescence

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

negative regulation of TORC1 signaling

3 references

9 May 2019

Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2-mediated suppression of mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13315

http://purl.uniprot.org/uniprot/Q13315

exact match

1 reference

1 reference

Telomere-length maintenance and DNA damage repair

1 reference

FATC domain

1 reference

PIK-related kinase, FAT

1 reference

Phosphatidylinositol 3/4-kinase, conserved site

1 reference

Phosphatidylinositol 3-/4-kinase, catalytic domain

1 reference