(Q14873936)

Nerve growth factor, beta subunit, mammalian

1 reference

Nerve growth factor-related, protein family

1 reference

based on heuristic

inferred from protein domain or family

Nerve growth factor conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

peptidase inhibitor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

enzyme inhibitor activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

transmembrane receptor protein tyrosine kinase activator activity

metalloendopeptidase inhibitor activity

3 references

signaling receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

endoplasmic reticulum lumen

cell component

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

2 references

1 reference

31 October 2017

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

neuron projection terminus

1 reference

14 February 2019

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

regulation of neuron differentiation

biological process

1 reference

31 October 2017

The novel neurotrophin-regulated neuronal development-associated protein, NDAP, mediates apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

neuron apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

negative regulation of peptidase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

peripheral nervous system development

1 reference

31 October 2017

Heterogeneous requirement of NGF for sympathetic target innervation in vivo

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

regulation of release of sequestered calcium ion into cytosol

1 reference

14 February 2019

Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of neurotrophin TRK receptor signaling pathway

1 reference

14 February 2019

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of DNA-binding transcription factor activity

1 reference

14 February 2019

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

regulation of neurotransmitter secretion

1 reference

14 February 2019

Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of collateral sprouting

1 reference

31 October 2017

The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

nerve growth factor signaling pathway

positive regulation of gene expression

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of protein autophosphorylation

IEP

1 reference

14 February 2019

The protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

extrinsic apoptotic signaling pathway in absence of ligand

1 reference

14 February 2019

Critical function of endogenous XIAP in regulating caspase activation during sympathetic neuronal apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of neuron projection development

3 references

14 February 2019

Nerve growth factor-dependent activation of the small GTPase Rin

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Spatially coordinated kinase signaling regulates local axon degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Spatially coordinated kinase signaling regulates local axon degeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of axon extension

positive regulation of protein ubiquitination

1 reference

14 February 2019

In vivo regulation of NGF-mediated functions by Nedd4-2 ubiquitination of TrkA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

extrinsic apoptotic signaling pathway via death domain receptors

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of protein phosphorylation

1 reference

31 October 2017

A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

sensory perception of pain

1 reference

31 October 2017

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

positive regulation of Ras protein signal transduction

1 reference

14 February 2019

Nerve growth factor-dependent activation of the small GTPase Rin

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

negative regulation of endopeptidase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

activation of transmembrane receptor protein tyrosine kinase activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

negative regulation of neuron apoptotic process

neuron projection morphogenesis

1 reference

31 October 2017

Spatial regulation of Raf kinase signaling by RKTG

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01139&geneProductId=UniProtKB:P01139

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of protein phosphorylation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

A TrkB/EphrinA interaction controls retinal axon branching and synaptogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of cell population proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

adult locomotory behavior

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of cell growth

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of protein binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

nerve growth factor signaling pathway

3 references

14 February 2019

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Cloning of a novel orphan receptor (GCNF) expressed during germ cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of DNA binding

1 reference

14 February 2019

Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

negative regulation of neuron apoptotic process

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Coronin-1 is a neurotrophin endosomal effector that is required for developmental competition for survival

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Populations of NGF-dependent neurones differ in their requirement for BAX to undergo apoptosis in the absence of NGF/TrkA signalling in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of neuron differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

1 reference

14 February 2019

The Protein Tyrosine Phosphatase MEG2 Regulates the Transport and Signal Transduction of Tropomyosin Receptor Kinase A.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of collateral sprouting

modulation of chemical synaptic transmission

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

positive regulation of stem cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

negative regulation of type B pancreatic cell apoptotic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01139

Nerve growth factor-related

has part(s)

1 reference

Nerve growth factor conserved site

1 reference

Encyclopædia Britannica Online ID

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

science/nerve-growth-factor

subject named as

nerve-growth factor

0 references

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016