(Q14902457)

http://www.ebi.ac.uk/interpro/protein/P39689

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

1 reference

24 April 2018

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

6 references

24 April 2018

A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Interaction of CR6 (GADD45gamma ) with proliferating cell nuclear antigen impedes negative growth control

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

protein kinase inhibitor activity

IPI

cyclin-dependent protein serine/threonine kinase activity

ISO

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

1 reference

24 April 2018

Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cyclin-dependent protein kinase holoenzyme complex

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

Hsc70 regulates accumulation of cyclin D1 and cyclin D1-dependent protein kinase

biological process

regulation of cell cycle

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

negative regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

24 April 2018

Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to arsenic-containing substance

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

1 reference

24 April 2018

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

regulation of DNA biosynthetic process

1 reference

24 April 2018

The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

animal organ regeneration

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

negative regulation of gene expression

1 reference

24 April 2018

The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to corticosterone

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

regulation of cyclin-dependent protein serine/threonine kinase activity

1 reference

24 April 2018

The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

positive regulation of programmed cell death

1 reference

24 April 2018

The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

intestinal epithelial cell maturation

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

1 reference

24 April 2018

Integral role of Noxa in p53-mediated apoptotic response

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cellular response to UV-B

1 reference

24 April 2018

A mouse model uncovers LKB1 as an UVB-induced DNA damage sensor mediating CDKN1A (p21WAF1/CIP1) degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to organic cyclic compound

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to glucocorticoid

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to hyperoxia

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to organonitrogen compound

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cellular response to heat

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

signal transduction by p53 class mediator

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to toxic substance

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

response to organic substance

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

Ras protein signal transduction

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

positive regulation of B cell proliferation

1 reference

24 April 2018

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cellular response to amino acid starvation

IGI

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cellular response to DNA damage stimulus

3 references

negative regulation of cell population proliferation

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

The Cdk inhibitor p21 is required for necrosis, but it inhibits apoptosis following toxin-induced liver injury

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

positive regulation of cyclin-dependent protein kinase activity

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

cellular response to gamma radiation

1 reference

24 April 2018

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

1 reference

24 April 2018

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

http://www.ebi.ac.uk/QuickGO/annotations?protein=P39689&geneProductId=UniProtKB:P39689