(Q24338238)

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Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

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Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress (English)

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Eukaryotic translation initiation factor 2 alpha kinase 4

1 reference

GOA release 2020-03-11

Cyclin dependent kinase inhibitor 1A

1 reference

GOA release 2020-03-11

regulation of translational initiation

1 reference

GOA release 2020-03-11

Eukaryotic translation initiation factor 2 alpha kinase 4

1 reference

GOA release 2020-03-11

Cyclin-dependent kinase inhibitor 1A (P21)

1 reference

GOA release 2020-03-11

4

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Europe PubMed Central

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13 June 2020

Costas Koumenis

6

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13 June 2020

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Stacey L Lehman

1

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13 June 2020

George J Cerniglia

2

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13 June 2020

Gregg J Johannes

3

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13 June 2020

Sandra Ryeom

5

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13 June 2020

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June 2015

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13 June 2020

11

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13 June 2020

e1005212

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13 June 2020

6

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13 June 2020

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Creative Commons Attribution 4.0 International

23 June 2015

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4477940/fullTextXML

based on heuristic

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A novel checkpoint mechanism regulating the G1/S transition

1 reference

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Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

1 reference

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A mammalian homologue of GCN2 protein kinase important for translational control by phosphorylation of eukaryotic initiation factor-2alpha

1 reference

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HuR regulates p21 mRNA stabilization by UV light

1 reference

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PERK mediates cell-cycle exit during the mammalian unfolded protein response

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19 March 2017

PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway

1 reference

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7 April 2017

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

1 reference

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Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα.

1 reference

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1 reference

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Serum-nutrient starvation induces cell death mediated by Bax and Puma that is counteracted by p21 and unmasked by Bcl-x(L) inhibition

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Phosphorylation of eIF2 facilitates ribosomal bypass of an inhibitory upstream ORF to enhance CHOP translation

1 reference

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27 September 2017

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1 reference

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27 September 2017

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27 September 2017

p21 in cancer: intricate networks and multiple activities

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Different mechanisms of cell death in radiosensitive and radioresistant p53 mutated head and neck squamous cell carcinoma cell lines exposed to carbon ions and x-rays

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27 September 2017

An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation

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Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

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A novel p21WAF1/CIP1 transcript is highly dependent on p53 for its basal expression in mouse tissues

1 reference

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Induction of p21 and p27 expression by amino acid deprivation of HepG2 human hepatoma cells involves mRNA stabilization

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Activation of the p21WAF1/CIP1 promoter independent of p53 by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through the Sp1 sites

1 reference

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1 reference

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1 reference

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https://pubmed.ncbi.nlm.nih.gov/26102367

12 December 2020

based on heuristic

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Identifiers

10.1371/JOURNAL.PGEN.1005212

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26102367%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

Europe PubMed Central

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13 June 2020

1 reference

Europe PubMed Central

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13 June 2020

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