(Q21105861)

Anticodon-binding domain superfamily

1 reference

eIF-2-alpha kinase Gcn2

1 reference

Ubiquitin-conjugating enzyme/RWD-like

1 reference

Histidyl tRNA synthetase-related domain, protein family

1 reference

RWD domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

image

EIF2AK4.png
1,920 × 975; 741 KB

0 references

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2K8&geneProductId=UniProtKB:Q9P2K8

protein kinase activity

1 reference

27 March 2018

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

2 references

eukaryotic translation initiation factor 2alpha kinase activity

3 references

27 March 2018

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2K8&geneProductId=UniProtKB:Q9P2K8

27 March 2018

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2K8&geneProductId=UniProtKB:Q9P2K8

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2K8&geneProductId=UniProtKB:Q9P2K8

eukaryotic translation initiation factor 2alpha kinase activity

4 references

8 April 2019

Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

8 April 2019

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9P2K8&geneProductId=UniProtKB:Q9P2K8

positive regulation of translational initiation in response to starvation

biological process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

adaptive immune response

1 reference

8 April 2019

negative regulation of neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

positive regulation of long-term synaptic potentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

positive regulation of adaptive immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

negative regulation of translational initiation in response to stress

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

negative regulation of translational initiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

immune system process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

cellular response to UV

1 reference

8 April 2019

negative regulation of CREB transcription factor activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

regulation of feeding behavior

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

neuron projection extension

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

cellular response to cold

1 reference

8 April 2019

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

defense response to virus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

cellular response to leucine starvation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

eiF2alpha phosphorylation in response to endoplasmic reticulum stress

1 reference

8 April 2019

p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

protein autophosphorylation

IMP

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

negative regulation by host of viral genome replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

regulation of translation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

regulation of translational initiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

positive regulation of defense response to virus by host

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

T cell activation involved in immune response

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

DNA damage checkpoint signaling

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

regulation of translational initiation by eIF2 alpha phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

8 April 2019

Translational Upregulation of an Individual p21Cip1 Transcript Variant by GCN2 Regulates Cell Proliferation and Survival under Nutrient Stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9P2K8

has part(s)

protein kinase domain

1 reference

protein kinase, ATP binding site

1 reference

Histidyl tRNA synthetase-related domain

1 reference

RWD domain

1 reference

serine/threonine-protein kinase, active site

1 reference