Wikidata

(Q14905787)

English

Hemojuvelin BMP co-receptor

mammalian protein found in Mus musculus

  • repulsive guidance molecule C
  • Hjv
  • hemochromatosis type 2 (juvenile) (human homolog)
  • hemochromatosis type 2 protein homolog
  • Hfe2
  • RGM domain family member C
  • hemojuvelin
  • hemojuvelin BMP coreceptor
In more languages

Statements

molecular function
cell component
biological process
iron ion homeostasis
determination method
IGI
IEA
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
ISO
retrieved
14 February 2019
stated in
Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Hemojuvelin is essential for transferrin-dependent and transferrin-independent hepcidin expression in mice
GOA
curator
Community Assessment of Community Annotation with Ontologies
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IEA
BMP signaling pathway
determination method
IGI
IEA
IMP
ISO
7 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
ISO
retrieved
24 April 2018
stated in
Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
24 April 2018
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
24 April 2018
stated in
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
24 April 2018
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q7TQ32&geneProductId=UniProtKB:Q7TQ32
determination method
IEA
positive regulation of transcription by RNA polymerase II
determination method
IDA
IGI
IEA
IMP
ISO
6 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
ISO
retrieved
14 February 2019
stated in
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Bmp6 expression in murine liver non parenchymal cells: a mechanism to control their high iron exporter activity and protect hepatocytes from iron overload?
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IEA
retrieved
14 February 2019
stated in
Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IDA
BMP signaling pathway
determination method
IBA
IEA
IGI
IMP
ISO
8 references
retrieved
14 February 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
ISO
retrieved
14 February 2019
stated in
Iron-dependent regulation of hepcidin in Hjv-/- mice: evidence that hemojuvelin is dispensable for sensing body iron levels
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IMP
retrieved
14 February 2019
stated in
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
14 February 2019
stated in
Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IGI
retrieved
14 February 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IEA
retrieved
14 February 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IEA
retrieved
14 February 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q7TQ32
determination method
IBA

Identifiers

 
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