(Q28507491)

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Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6

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24 January 2017

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6 (English)

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24 January 2017

Hemojuvelin BMP co-receptor

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stated in

GOA release 2020-03-11

Transmembrane serine protease 6

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stated in

GOA release 2020-03-11

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5

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author name string

Jaroslav Truksa

series ordinal

1

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24 January 2017

Terri Gelbart

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2

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24 January 2017

Hongfan Peng

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3

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24 January 2017

Ernest Beutler

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4

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24 January 2017

Pauline Lee

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6

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24 January 2017

language of work or name

English

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publication date

1 November 2009

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24 January 2017

British Journal of Haematology

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24 January 2017

147

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24 January 2017

4

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24 January 2017

571–581

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24 January 2017

Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Naturally variant autosomal and sex-linked loci determine the severity of iron overload in beta 2-microglobulin-deficient mice

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

The IL-6- and lipopolysaccharide-induced transcription of hepcidin in HFE-, transferrin receptor 2-, and beta 2-microglobulin-deficient hepatocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Juvenile hemochromatosis.

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Two BMP responsive elements, STAT, and bZIP/HNF4/COUP motifs of the hepcidin promoter are critical for BMP, SMAD1, and HJV responsiveness

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

The serine protease TMPRSS6 is required to sense iron deficiency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

A mouse model of juvenile hemochromatosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Two nonsense mutations in the TMPRSS6 gene in a patient with microcytic anemia and iron deficiency

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Membrane-bound serine protease matriptase-2 (Tmprss6) is an essential regulator of iron homeostasis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

In vivo imaging of hepcidin promoter stimulation by iron and inflammation

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Spectrum of hemojuvelin gene mutations in 1q-linked juvenile hemochromatosis.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

Natural history of juvenile haemochromatosis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

The distal location of the iron responsive region of the hepcidin promoter.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1365-2141.2009.07873.X

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DOI

10.1111/J.1365-2141.2009.07873.X

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1 reference

24 January 2017

ResearchGate publication ID

26809286

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(Q28507491)

Suppression of the hepcidin-encoding gene Hamp permits iron overload in mice lacking both hemojuvelin and matriptase-2/TMPRSS6

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