Wikidata

(Q14906022)

English

Eukaryotic translation initiation factor 2-alpha kinase 2

mammalian protein found in Mus musculus

  • 2.7.10.2
  • IFN- type I-induced and dsRNA-activated kinase
  • interferon-induced, double-stranded RNA-activated protein kinase
  • interferon-inducible RNA-dependent protein kinase
  • Eif2ak2
  • eIF-2A protein kinase 2
  • eIF-2 alpha
  • PKR
  • P1/eIF-2A protein kinase
  • protein kinase RNA-activated
  • p68 kinase
  • protein kinase R
  • protein kinase, interferon-inducible double stranded RNA dependent
  • tyrosine-protein kinase EIF2AK2
  • IFN-induced and double-stranded RNA-activated kinase
  • serine/threonine-protein kinase TIK
  • dsRNA-activated kinase
  • T-cell viral integration site
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No label defined

No description defined

Statements

molecular function
protein kinase activity
determination method or standard
IDA
IEA
IMP
ISO
6 references
retrieved
24 April 2018
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
ISO
retrieved
24 April 2018
stated in
Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense
GOA
curator
UniProt
UniProt protein ID
Q03963
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
IMP
retrieved
24 April 2018
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
IEA
retrieved
24 April 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
IEA
retrieved
24 April 2018
stated in
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
IDA
retrieved
24 April 2018
stated in
Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=Q03963&geneProductId=UniProtKB:Q03963
determination method or standard
IDA
protein binding
determination method or standard
IPI
7 references
retrieved
9 May 2019
stated in
Nucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKR
GOA
curator
UniProt
UniProt protein ID
Q03963
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
The editing enzyme ADAR1 and the mRNA surveillance protein hUpf1 interact in the cell nucleus
GOA
curator
UniProt
UniProt protein ID
Q03963
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
Novel role of PKR in inflammasome activation and HMGB1 release
GOA
curator
UniProt
UniProt protein ID
Q03963
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
JAZ requires the double-stranded RNA-binding zinc finger motifs for nuclear localization
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
retrieved
9 May 2019
stated in
Novel role of PKR in inflammasome activation and HMGB1 release
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IPI
protein kinase activity
determination method or standard
IBA
IDA
IEA
IMP
ISO
7 references
retrieved
9 May 2019
stated in
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
ISO
retrieved
9 May 2019
stated in
Phosphorylation of the NFAR proteins by the dsRNA-dependent protein kinase PKR constitutes a novel mechanism of translational regulation and cellular defense
GOA
curator
UniProt
UniProt protein ID
Q03963
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IMP
retrieved
9 May 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IEA
retrieved
9 May 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IEA
retrieved
9 May 2019
stated in
Loss of alpha-hemoglobin-stabilizing protein impairs erythropoiesis and exacerbates beta-thalassemia
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IDA
retrieved
9 May 2019
stated in
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IDA
retrieved
9 May 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q03963
determination method or standard
IBA
cell component
biological process

Identifiers

 
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