(Q24293509)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Novel role of PKR in inflammasome activation and HMGB1 release (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

Eukaryotic translation initiation factor 2 alpha kinase 2

8 February 2020

main subject

1 reference

protein autophosphorylation

1 reference

NLR family, pyrin domain containing 3

1 reference

Eukaryotic translation initiation factor 2-alpha kinase 2

1 reference

Caspase 1

1 reference

PYD and CARD domain containing

1 reference

1 reference

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ulf Andersson

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Haichao Wang

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Kevin J. Tracey

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Takahisa Nakamura

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Sergio I Valdés-Ferrer

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

18

Sangeeta S Chavan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

19

Gökhan S Hotamisligil

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

5

Yiting Tang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

8

Peder S Olofsson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

10

Jesse Roth

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Helena Erlandsson-Harris

12

object named as

Helena Erlandsson-Harris

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

17

Daniel J Antoine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Ben Lu

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Karen Inouye

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jianhua Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Thomas Kalb

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Yongrui Zou

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Huan Yang

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Jenny P-Y Ting

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

1 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

488

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

7413

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

670-674

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

8 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Regulation of inflammasome signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Gout-associated uric acid crystals activate the NALP3 inflammasome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Non-canonical inflammasome activation targets caspase-11

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

HMGB proteins function as universal sentinels for nucleic-acid-mediated innate immune responses

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Inflammasomes in health and disease

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Sensing and reacting to microbes through the inflammasomes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

The PYHIN protein family as mediators of host defenses.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Modulation of inflammasome pathways by bacterial and viral pathogens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Cutting edge: reactive oxygen species inhibitors block priming, but not activation, of the NLRP3 inflammasome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

HMGB1 is a therapeutic target for sterile inflammation and infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Inflammasome-dependent release of the alarmin HMGB1 in endotoxemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Cryopyrin/NALP3 binds ATP/dATP, is an ATPase, and requires ATP binding to mediate inflammatory signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

The relationship between apoptosis and high-mobility group protein 1 release from murine macrophages stimulated with lipopolysaccharide or polyinosinic-polycytidylic acid

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

The inflammasome: first line of the immune response to cell stress

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Role of HMGB1 in apoptosis-mediated sepsis lethality

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4163918

Maturing dendritic cells depend on RAGE for in vivo homing to lymph nodes

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22801494

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE11290

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 February 2020

1042672523

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

22801494

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22801494%20AND%20SRC:MED&resulttype=core&format=json