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Regulation of inflammasome signaling
scientific article
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scholarly article
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stated in
PubMed
title
Regulation of inflammasome signaling
(English)
0 references
main subject
inflammasome complex
1 reference
based on heuristic
inferred from title
author name string
Vijay A K Rathinam
series ordinal
1
1 reference
stated in
Crossref
Sivapriya Kailasan Vanaja
series ordinal
2
1 reference
stated in
Crossref
Katherine A Fitzgerald
series ordinal
3
1 reference
stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
19 March 2012
1 reference
stated in
PubMed
published in
Nature Immunology
1 reference
stated in
PubMed
volume
13
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stated in
PubMed
issue
4
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stated in
PubMed
page(s)
333-42
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stated in
PubMed
cites work
IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes
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Molecular mechanisms of inflammasome activation during microbial infections
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21 March 2017
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection
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21 March 2017
Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions
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21 March 2017
IFI16 is an innate immune sensor for intracellular DNA
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21 March 2017
Neisseria gonorrhoeae activates the proteinase cathepsin B to mediate the signaling activities of the NLRP3 and ASC-containing inflammasome
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21 March 2017
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
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21 March 2017
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
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21 March 2017
Trex1 prevents cell-intrinsic initiation of autoimmunity
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21 March 2017
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
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21 March 2017
Active caspase-1 is a regulator of unconventional protein secretion
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Mutations in NALP12 cause hereditary periodic fever syndromes
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Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
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21 March 2017
Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions
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21 March 2017
Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation
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21 March 2017
The estrogen-responsive B box protein: a novel enhancer of interleukin-1beta secretion
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21 March 2017
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals
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The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation
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21 March 2017
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
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21 March 2017
PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing
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21 March 2017
The serpin proteinase inhibitor 9 is an endogenous inhibitor of interleukin 1beta-converting enzyme (caspase-1) activity in human vascular smooth muscle cells
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21 March 2017
Structural basis of RNA recognition and activation by innate immune receptor RIG-I
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21 March 2017
Structure and Interdomain Dynamics of Apoptosis-associated Speck-like Protein Containing a CARD (ASC)
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21 March 2017
A role for mitochondria in NLRP3 inflammasome activation
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21 March 2017
NALPs: a novel protein family involved in inflammation
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21 March 2017
Central roles of NLRs and inflammasomes in viral infection
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21 March 2017
Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes
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21 March 2017
Influenza virus activates inflammasomes via its intracellular M2 ion channel
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21 March 2017
Co-regulation of NF-kappaB and inflammasome-mediated inflammatory responses by myxoma virus pyrin domain-containing protein M013
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21 March 2017
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain
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21 March 2017
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
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21 March 2017
Cryopyrin activates the inflammasome in response to toxins and ATP
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21 March 2017
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
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21 March 2017
CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain
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21 March 2017
Non-canonical inflammasome activation targets caspase-11
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21 March 2017
The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization
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21 March 2017
Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity
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21 March 2017
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
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21 March 2017
Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production
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21 March 2017
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity
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21 March 2017
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
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21 March 2017
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide
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21 March 2017
Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA
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21 March 2017
Autophagy-based unconventional secretory pathway for extracellular delivery of IL-1β
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7 April 2017
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
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7 April 2017
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis
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7 April 2017
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
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7 April 2017
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
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7 April 2017
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
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7 April 2017
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
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7 April 2017
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis
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7 April 2017
Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection
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28 September 2017
The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.
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28 September 2017
Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.
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28 September 2017
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
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28 September 2017
The PYHIN protein family as mediators of host defenses.
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28 September 2017
Gain-of-function Pyrin mutations induce NLRP3 protein-independent interleukin-1β activation and severe autoinflammation in mice
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28 September 2017
Inflammasome-independent modulation of cytokine response by autophagy in human cells
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28 September 2017
Discovery of a viral NLR homolog that inhibits the inflammasome
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28 September 2017
Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation
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28 September 2017
Differential requirement for Caspase-1 autoproteolysis in pathogen-induced cell death and cytokine processing
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28 September 2017
Apoptosis-associated speck-like protein (ASC) controls Legionella pneumophila infection in human monocytes
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28 September 2017
Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.
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28 September 2017
Deletion of ripA alleviates suppression of the inflammasome and MAPK by Francisella tularensis
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28 September 2017
Regulation of interleukin-1beta by interferon-gamma is species specific, limited by suppressor of cytokine signalling 1 and influences interleukin-17 production
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28 September 2017
Molecular mechanism of NLRP3 inflammasome activation
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28 September 2017
Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1
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28 September 2017
A Yersinia effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system
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28 September 2017
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.
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28 September 2017
Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity
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28 September 2017
Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome
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28 September 2017
Intracellular DNA recognition
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28 September 2017
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1beta, depending on listeriolysin O and NLRP3.
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28 September 2017
CA-074Me protection against anthrax lethal toxin
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28 September 2017
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
An essential role for the NLRP3 inflammasome in host defense against the human fungal pathogen Candida albicans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Mycobacterium tuberculosis prevents inflammasome activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
The Pseudomonas aeruginosa Type III secretion system plays a dual role in the regulation of caspase-1 mediated IL-1beta maturation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Type I interferon signaling is required for activation of the inflammasome during Francisella infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Monarch-1/PYPAF7 and other CATERPILLER (CLR, NOD, NLR) proteins with negative regulatory functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Monarch-1 suppresses non-canonical NF-kappaB activation and p52-dependent chemokine expression in monocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
CATERPILLERs, pyrin and hereditary immunological disorders
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Targeting Rac1 by the Yersinia effector protein YopE inhibits caspase-1-mediated maturation and release of interleukin-1beta
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
A candidate gene for familial Mediterranean fever
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Characterization of a myxoma virus-encoded serpin-like protein with activity against interleukin-1 beta-converting enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Viral inhibition of inflammation: cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 September 2017
Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
31 May 2018
Cutting edge: mutation of Francisella tularensis mviN leads to increased macrophage absent in melanoma 2 inflammasome activation and a loss of virulence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
31 May 2018
Listeria monocytogenes is sensed by the NLRP3 and AIM2 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
31 May 2018
Streptococcus pneumoniae evades human dendritic cell surveillance by pneumolysin expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
31 May 2018
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
31 May 2018
The NLRP3 Inflammasome Is Differentially Activated by Pneumolysin Variants and Contributes to Host Defense in Pneumococcal Pneumonia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Emerging inflammasome effector mechanisms.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Different evolutionary strategies for the origin of caspase-1 inhibitors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
A poxvirus-encoded pyrin domain protein interacts with ASC-1 to inhibit host inflammatory and apoptotic responses to infection.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Toll-like receptor-independent gene induction program activated by mammalian DNA escaped from apoptotic DNA degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3523703
retrieved
28 November 2018
Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22430786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22430786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of interleukin-1β in NLRP12-associated autoinflammatory disorders and resistance to anti-interleukin-1 therapy
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22430786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22430786
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dextran sulfate sodium and 2,4,6-trinitrobenzene sulfonic acid induce lipid peroxidation by the proliferation of intestinal gram-negative bacteria in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNI.2237
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NI.2237
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
357837
OpenCitations bibliographic resource ID
357837
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
357837
PMC publication ID
3523703
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
357837
PubMed publication ID
22430786
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
357837
ResearchGate publication ID
221723430
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