(Q29547419)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome (English)

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

0 references

1 reference

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

13

Augustine M K Choi

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

12

Stefan W Ryter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1

Kiichi Nakahira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Jeffrey Adam Haspel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Vijay A K Rathinam

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Seon-Jin Lee

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Tamas Dolinay

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Hilaire C Lam

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Marlene Rabinovitch

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Manuela Cernadas

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Hong Pyo Kim

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Katherine A Fitzgerald

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

18 January 2020

language of work or name

1 reference

23 April 2017

publication date

12 December 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

18 January 2020

number of pages

9

1 reference

based on heuristic

inferred from page(s)

2 references

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

12

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

3

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

222-230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

IFI16 is an innate immune sensor for intracellular DNA

18 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Loss of autophagy in erythroid cells leads to defective removal of mitochondria and severe anemia in vivo

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Inflammasomes: too big to miss

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Regulation mechanisms and signaling pathways of autophagy

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mitochondrial calcium and the permeability transition in cell death

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Autophagy in the Pathogenesis of Disease

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Developmental expression of LC3α and β: Absence of fibronectin or autophagy phenotype in LC3β knockout mice

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Nonclassical IL-1 beta secretion stimulated by P2X7 receptors is dependent on inflammasome activation and correlated with exosome release in murine macrophages

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mitochondrial membrane permeabilization in cell death

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Role of sodium in mitochondrial membrane depolarization induced by P2X7 receptor activation in submandibular glands

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

23 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

23 April 2017

https://api.crossref.org/works/10.1038%2FNI.1980

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

25 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Circulating mitochondrial DAMPs cause inflammatory responses to injury

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mitochondrial respiratory-chain diseases

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis.

23 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Intracellular DNA recognition

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

A mitochondria-targeted triphenylphosphonium-conjugated nitroxide functions as a radioprotector/mitigator

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mitochondrial dynamics in mammalian health and disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Autophagy genes in immunity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Sepsis induces extensive autophagic vacuolization in hepatocytes: a clinical and laboratory-based study

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Inflammasome mRNA expression in human monocytes during early septic shock

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Monitoring autophagy in glioblastoma with antibody against isoform B of human microtubule-associated protein 1 light chain 3.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Heme oxygenase-1-derived carbon monoxide enhances the host defense response to microbial sepsis in mice

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Ataxia-telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Basal activation of the P2X7 ATP receptor elevates mitochondrial calcium and potential, increases cellular ATP levels, and promotes serum-independent growth

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Cells depleted of mitochondrial DNA (rho0) yield insight into physiological mechanisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Establishment of human cell lines lacking mitochondrial DNA.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Antioxidant properties of MitoTEMPOL and its hydroxylamine.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Sepsis induces brain mitochondrial dysfunction

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3079381

Superoxide dismutase 1 regulates caspase-1 and endotoxic shock

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21151103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

3 references

23 April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21151103%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

3 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21151103

23 April 2017