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The inflammasomes
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instance of
scholarly article
0 references
review article
1 reference
stated in
Europe PubMed Central
title
The inflammasomes
(English)
0 references
main subject
IPAF inflammasome complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0072557
NLRP1 inflammasome complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0072558
NLRP3 inflammasome complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0072559
AIM2 inflammasome complex
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0097169
NLR family pyrin domain containing 1
1 reference
stated in
GOA release 2020-03-11
inflammasome complex
1 reference
based on heuristic
inferred from title
author
Kate Schroder
series ordinal
1
0 references
Jürg Tschopp
series ordinal
2
object named as
Jurg Tschopp
0 references
language of work or name
English
0 references
publication date
19 March 2010
0 references
published in
Cell
0 references
volume
140
0 references
page(s)
821-32
0 references
issue
6
0 references
cites work
Spectrum of clinical features in Muckle-Wells syndrome and response to anakinra
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Successful treatment of resistant pseudogout with anakinra.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
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inferred from DOI database lookup
A pilot study to evaluate the safety and efficacy of the long-acting interleukin-1 inhibitor rilonacept (interleukin-1 Trap) in patients with familial cold autoinflammatory syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy and safety of rilonacept (interleukin-1 Trap) in patients with cryopyrin-associated periodic syndromes: results from two sequential placebo-controlled studies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role for Ipaf in Pseudomonas aeruginosa-induced caspase-1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TLR5 and Ipaf: dual sensors of bacterial flagellin in the innate immune system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 and Bcl-XL regulate proinflammatory caspase-1 activation by interaction with NALP1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy, Immunity, and Microbial Adaptations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shigella phagocytic vacuolar membrane remnants participate in the cellular response to pathogen invasion and are regulated by autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NLR gene family: a standard nomenclature
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammasome-mediated disease animal models reveal roles for innate but not adaptive immunity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reconstituted NALP1 inflammasome reveals two-step mechanism of caspase-1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of active oxygen species and NO in plant defence responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide is the major reactive oxygen species regulating autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of intracellular ROS levels by TIGAR controls autophagy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cryopyrin activates the inflammasome in response to toxins and ATP
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Gout-associated uric acid crystals activate the NALP3 inflammasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NLRX1 is a regulator of mitochondrial antiviral immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CARD15 mutations in Blau syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1beta via Ipaf
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NALP3 inflammasome is involved in the innate immune response to amyloid-beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NALPs: a novel protein family involved in inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyroptosis: host cell death and inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammatory caspases and inflammasomes: master switches of inflammation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the IL-1β-Processing Inflammasome Is Involved in Contact Hypersensitivity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of TXNIP protects beta-cells against glucotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NALP1 in vitiligo-associated multiple autoimmune disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Use of canakinumab in the cryopyrin-associated periodic syndrome
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in NALP12 cause hereditary periodic fever syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pseudomonas aeruginosa activates caspase 1 through Ipaf
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Txnip balances metabolic and growth signaling via PTEN disulfide reduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Nalp3 inflammasome is essential for the development of silicosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of Bcl-2 and Bcl-X(L) inhibition of NLRP1 inflammasome: loop domain-dependent suppression of ATP binding and oligomerization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of antibacterial autophagy by NADPH oxidases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Injection of flagellin into the host cell cytosol by Salmonella enterica serotype Typhimurium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential requirement of P2X7 receptor and intracellular K+ for caspase-1 activation induced by intracellular and extracellular bacteria.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo regulation of interleukin 1beta in patients with cryopyrin-associated periodic syndromes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spread of an inactive form of caspase-12 in humans is due to recent positive selection
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Autophagy and the immune response to TB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The NLRP3 inflammasome: a sensor for metabolic danger?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CA-074Me protection against anthrax lethal toxin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Asc and Ipaf Inflammasomes direct distinct pathways for caspase-1 activation in response to Legionella pneumophila
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of a functional NF-kappa B site in the human interleukin 1 beta promoter: evidence for a positive autoregulatory loop
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Management of treatment resistant inflammation of acute on chronic tophaceous gout with anakinra
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The inflammasomes: guardians of the body
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tolerance, danger, and the extended family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
SERUM URATE IN RELATIVES OF GOUTY PATIENTS.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pilot study of IL-1 inhibition by anakinra in acute gout
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Innate immune sensing of microbes by Nod proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Germline mutation in NLRP2 (NALP2) in a familial imprinting disorder (Beckwith-Wiedemann Syndrome).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TXNIP regulates peripheral glucose metabolism in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Malarial hemozoin is a Nalp3 inflammasome activating danger signal
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The future of the IL-1 receptor antagonist anakinra: from rheumatoid arthritis to adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rilonacept for the treatment of cryopyrin-associated periodic syndromes (CAPS)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-1 beta targeted therapy for type 2 diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sustained effects of interleukin-1 receptor antagonist treatment in type 2 diabetes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A role for Nod-like receptors in autophagy induced by Shigella infection.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.CELL.2010.01.040
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/J.CELL.2010.01.040
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
39335
OpenCitations bibliographic resource ID
39335
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
39335
PubMed ID
20303873
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
39335
ResearchGate publication ID
42370834
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