(Q36405072)

14 August 2017

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title

CATERPILLERs, pyrin and hereditary immunological disorders (English)

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14 August 2017

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2

Daniel L Kastner

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14 August 2017

Jenny P-Y Ting

1

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14 August 2017

Hal M Hoffman

series ordinal

3

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14 August 2017

publication date

1 March 2006

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Nature Reviews Immunology

14 August 2017

published in

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14 August 2017

volume

6

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14 August 2017

issue

3

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14 August 2017

page(s)

183-195

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Establishment of dorsal-ventral polarity in the Drosophila embryo: genetic studies on the role of the Toll gene product.

14 August 2017

cites work

1 reference

The immune response of Drosophila

21 January 2018

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A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

21 January 2018

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Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 January 2018

1 reference

Class II transactivator: mastering the art of major histocompatibility complex expression

21 January 2018

1 reference

The NOD: a signaling module that regulates apoptosis and host defense against pathogens

21 January 2018

1 reference

Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains

21 January 2018

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CATERPILLER: a novel gene family important in immunity, cell death, and diseases

21 January 2018

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

21 January 2018

1 reference

NODs: intracellular proteins involved in inflammation and apoptosis

21 January 2018

1 reference

NOD-LRR proteins: role in host-microbial interactions and inflammatory disease

21 January 2018

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NLRs join TLRs as innate sensors of pathogens

21 January 2018

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The NACHT family - a new group of predicted NTPases implicated in apoptosis and MHC transcription activation

21 January 2018

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The gene for neuronal apoptosis inhibitory protein is partially deleted in individuals with spinal muscular atrophy

21 January 2018

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PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 January 2018

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A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta

21 January 2018

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NALPs: a novel protein family involved in inflammation

21 January 2018

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The PYRIN connection: novel players in innate immunity and inflammation

21 January 2018

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Are innate immune signaling pathways in plants and animals conserved?

21 January 2018

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

21 January 2018

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Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

21 January 2018

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Structure of the apoptotic protease-activating factor 1 bound to ADP

21 January 2018

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Genetic control of MHC class II expression

21 January 2018

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The bare lymphocyte syndrome and the regulation of MHC expression

21 January 2018

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MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction

21 January 2018

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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome

21 January 2018

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Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis

21 January 2018

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New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes

21 January 2018

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Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

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CARD15 mutations in Blau syndrome

21 January 2018

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A candidate gene for familial Mediterranean fever

21 January 2018

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Familial autoinflammatory diseases: genetics, pathogenesis and treatment

21 January 2018

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Mini-review: the role of peptidoglycan recognition in innate immunity

21 January 2018

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PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion

21 January 2018

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PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages

21 January 2018

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The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals

21 January 2018

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PYPAF7, a novel PYRIN-containing Apaf1-like protein that regulates activation of NF-kappa B and caspase-1-dependent cytokine processing

21 January 2018

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Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.

21 January 2018

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Cryopyrin and pyrin activate caspase-1, but not NF-kappaB, via ASC oligomerization.

21 January 2018

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NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses

21 January 2018

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Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

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Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

21 January 2018

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When the Lymphocyte Loses Its Clothes

21 January 2018

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The bare lymphocyte syndrome: molecular clues to the transcriptional regulation of major histocompatibility complex class II genes

21 January 2018

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Coordinate defects in human histocompatibility leukocyte antigen class II expression and antigen presentation in bare lymphocyte syndrome.

21 January 2018

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Clinical course of patients with major histocompatibility complex class II deficiency

21 January 2018

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Induction of MHC class I expression by the MHC class II transactivator CIITA.

21 January 2018

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Absence of MHC class II gene expression in a patient with a single amino acid substitution in the class II transactivator protein CIITA.

21 January 2018

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Mutation in the class II trans-activator leading to a mild immunodeficiency

21 January 2018

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Regulation of MHC class II gene expression by the class II transactivator

21 January 2018

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Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA).

21 January 2018

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Epigenetic control of MHC-II: interplay between CIITA and histone-modifying enzymes

21 January 2018

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Transcriptional scaffold: CIITA interacts with NF-Y, RFX, and CREB to cause stereospecific regulation of the class II major histocompatibility complex promoter

21 January 2018

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Associations and interactions between bare lymphocyte syndrome factors

21 January 2018

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Two distinct domains within CIITA mediate self-association: involvement of the GTP-binding and leucine-rich repeat domains

21 January 2018

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Self-association of CIITA and its transactivation potential

21 January 2018

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CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation

21 January 2018

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Leucine-rich repeats of the class II transactivator control its rate of nuclear accumulation.

21 January 2018

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Importance of class II transactivator leucine-rich repeats for dominant-negative function and nucleo-cytoplasmic transport

21 January 2018

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Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator

21 January 2018

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Interactions between the class II transactivator and CREB binding protein increase transcription of major histocompatibility complex class II genes

21 January 2018

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Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression

21 January 2018

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CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo

21 January 2018

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CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter

21 January 2018

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Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250

21 January 2018

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Histone Deacetylase 1/mSin3A Disrupts Gamma Interferon-Induced CIITA Function and Major Histocompatibility Complex Class II Enhanceosome Formation

21 January 2018

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Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases

21 January 2018

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GTP binding by class II transactivator: role in nuclear import

21 January 2018

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Self-association of class II transactivator correlates with its intracellular localization and transactivation

21 January 2018

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Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters

21 January 2018

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The GTP-binding domain of class II transactivator regulates its nuclear export

21 January 2018

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De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases

21 January 2018

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Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes

21 January 2018

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Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever

21 January 2018

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NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

21 January 2018

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IL-converting enzyme/caspase-1 inhibitor VX-765 blocks the hypersensitive response to an inflammatory stimulus in monocytes from familial cold autoinflammatory syndrome patients

21 January 2018

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Structural, expression, and evolutionary analysis of mouse CIAS1

21 January 2018

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Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-kappaB

21 January 2018

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Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease

21 January 2018

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Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product

21 January 2018

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The PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathways

21 January 2018

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Cutting edge: CIAS1/cryopyrin/PYPAF1/NALP3/CATERPILLER 1.1 is an inducible inflammatory mediator with NF-kappa B suppressive properties

21 January 2018

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Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 January 2018

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Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

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Gout-associated uric acid crystals activate the NALP3 inflammasome

21 January 2018

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The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

21 January 2018

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Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC

21 January 2018

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Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome.

21 January 2018

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Crohn disease in patients with familial Mediterranean fever

21 January 2018

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Identification of a mutation in the gene causing hyperkalemic periodic paralysis

21 January 2018

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Higher than expected carrier rates for familial Mediterranean fever in various Jewish ethnic groups

21 January 2018

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Familial Mediterranean fever: prevalence, penetrance and genetic drift

21 January 2018

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Common MEFV mutations among Jewish ethnic groups in Israel: high frequency of carrier and phenotype III states and absence of a perceptible biological advantage for the carrier state

21 January 2018

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Mutation frequency of Familial Mediterranean Fever and evidence for a high carrier rate in the Turkish population

21 January 2018

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Specific glycosylation of alpha(1)-acid glycoprotein characterises patients with familial Mediterranean fever and obligatory carriers of MEFV

21 January 2018

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Episodic evolution of pyrin in primates: human mutations recapitulate ancestral amino acid states

21 January 2018

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Isolation, genomic organization, and expression analysis of the mouse and rat homologs of MEFV, the gene for familial mediterranean fever

21 January 2018

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Lipopolysaccharide-induced expression of multiple alternatively spliced MEFV transcripts in human synovial fibroblasts: a prominent splice isoform lacks the C-terminal domain that is highly mutated in familial Mediterranean fever

21 January 2018

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The familial mediterranean fever protein interacts and colocalizes with a putative Golgi transporter

21 January 2018

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Alternative splicing at the MEFV locus involved in familial Mediterranean fever regulates translocation of the marenostrin/pyrin protein to the nucleus

21 January 2018

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The familial Mediterranean fever protein, pyrin, associates with microtubules and colocalizes with actin filaments

21 January 2018

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The PYRIN domain: a novel motif found in apoptosis and inflammation proteins

21 January 2018

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Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis

21 January 2018

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Targeted disruption of pyrin, the FMF protein, causes heightened sensitivity to endotoxin and a defect in macrophage apoptosis

21 January 2018

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ASC is an activating adaptor for NF-kappa B and caspase-8-dependent apoptosis

21 January 2018

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TRIM5alpha mediates the postentry block to N-tropic murine leukemia viruses in human cells

21 January 2018

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Retrovirus restriction by TRIM5alpha variants from Old World and New World primates

21 January 2018

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Interleukin-1-receptor antagonist in the Muckle-Wells syndrome.

21 January 2018

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Interleukin-1 blockade by anakinra improves clinical symptoms in patients with neonatal-onset multisystem inflammatory disease

21 January 2018

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Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist

21 January 2018

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TIR domain-containing adaptors regulate TLR signaling pathways

21 January 2018

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Toll-like receptors: linking innate and adaptive immunity

31 March 2020

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Genetic analysis of innate immunity: identification and function of the TIR adapter proteins

31 March 2020

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Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever

31 March 2020

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CATERPILLER 16.2 (CLR16.2), a novel NBD/LRR family member that negatively regulates T cell function

31 March 2020

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Signalling pathways and molecular interactions of NOD1 and NOD2

31 March 2020

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T cell development in a major histocompatibility complex class II-deficient patient

31 March 2020

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Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA

31 March 2020

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A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome

31 March 2020

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In vivo footprinting of MHC class II genes: bare promoters in the bare lymphocyte syndrome

31 March 2020

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The 'Muckle–Wells' syndrome

31 March 2020

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Molecular basis of the spectral expression of CIAS1 mutations associated with phagocytic cell-mediated autoinflammatory disorders CINCA/NOMID, MWS, and FCU

31 March 2020

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Familial Mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study

31 March 2020

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MEFV gene is a probable susceptibility gene for Behçet's disease

31 March 2020

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Inflammatory bowel disease in non-Ashkenazi Jews with familial Mediterranean fever

31 March 2020

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Acute phase response and evolution of familial Mediterranean fever

31 March 2020

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Interaction of pyrin with 14.3.3 in an isoform-specific and phosphorylation-dependent manner regulates its translocation to the nucleus

31 March 2020

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A provisional transcript map of the spinal muscular atrophy (SMA) critical region

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRI1788

1 reference

14 August 2017

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