(Q14907300)

SAND-like domain superfamily

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

Autoimmune regulator, AIRE

1 reference

Zinc finger, PHD-finger, protein family

1 reference

HSR domain, protein family

1 reference

Zinc finger, PHD-type, protein family

1 reference

SAND domain, protein family

1 reference

Zinc finger, PHD-type, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

1 reference

25 May 2022

1 reference

25 May 2022

2 references

4 references

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

RNA polymerase II transcription regulatory region sequence-specific DNA binding

3 references

transcription coregulator activity

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

translation regulator activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

identical protein binding

IEA

1 reference

14 February 2019

The autoimmune regulator (AIRE) is a DNA-binding protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

intracellular anatomical structure

1 reference

10 September 2018

Modulation of Aire regulates the expression of tissue-restricted antigens

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

1 reference

14 February 2019

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Subcellular location and expression pattern of autoimmune regulator (Aire), the mouse orthologue for human gene defective in autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

positive regulation of transcription, DNA-templated

biological process

3 references

regulation of translation

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

transcription, DNA-templated

IEA

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

positive regulation of transcription by RNA polymerase II

IEA

4 references

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

Modulation of Aire regulates the expression of tissue-restricted antigens

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

27 March 2018

Modulation of Aire regulates the expression of tissue-restricted antigens

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

negative thymic T cell selection

1 reference

27 March 2018

Macroautophagy substrates are loaded onto MHC class II of medullary thymic epithelial cells for central tolerance

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

peripheral T cell tolerance induction

IGI

1 reference

27 March 2018

Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

central tolerance induction to self antigen

1 reference

27 March 2018

Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

thymus epithelium morphogenesis

1 reference

27 March 2018

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

regulation of thymocyte migration

1 reference

27 March 2018

Autoimmune regulator deficiency results in decreased expression of CCR4 and CCR7 ligands and in delayed migration of CD4+ thymocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9Z0E3&geneProductId=UniProtKB:Q9Z0E3

peripheral T cell tolerance induction

central tolerance induction to self antigen

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

humoral immune response

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

positive regulation of transcription by RNA polymerase II

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Modulation of Aire regulates the expression of tissue-restricted antigens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Modulation of Aire regulates the expression of tissue-restricted antigens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Z0E3

thymus epithelium morphogenesis

regulation of thymocyte migration

Zinc finger, PHD-type, conserved site

1 reference

Zinc finger, PHD-finger

1 reference

Zinc finger, PHD-type

1 reference

HSR domain

1 reference

SAND domain

1 reference