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Modulation of Aire regulates the expression of tissue-restricted antigens
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
title
Modulation of Aire regulates the expression of tissue-restricted antigens
(English)
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
main subject
Epithelial cell adhesion molecule
1 reference
stated in
GOA release 2020-03-11
Autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
1 reference
stated in
GOA release 2020-03-11
author
Kai Kisand
object named as
Kai Kisand
series ordinal
3
0 references
Pärt Peterson
object named as
Pärt Peterson
series ordinal
6
0 references
Andres Merits
object named as
Andres Merits
series ordinal
4
0 references
Hamish S. Scott
object named as
Hamish S. Scott
series ordinal
5
0 references
Vivian Kont
series ordinal
1
object named as
Vivian Kont
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
author name string
Martti Laan
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
1 January 2008
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
published in
Molecular Immunology
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
volume
45
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stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
page(s)
25–33
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stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
issue
1
1 reference
stated in
PubMed
PubMed ID
17599412
retrieved
24 January 2017
cites work
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PubMed Central
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Aire regulates negative selection of organ-specific T cells
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Projection of an immunological self shadow within the thymus by the aire protein
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Aire deficient mice develop multiple features of APECED phenotype and show altered immune response
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Cell type specific expression of secretory TFF peptides: colocalization with mucins and synthesis in the brain
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The autoimmune regulator (AIRE) is a DNA-binding protein
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Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED)
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PubMed Central
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The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein
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PubMed Central
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Positional cloning of the APECED gene
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PubMed Central
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NF-kappaB2 is required for the control of autoimmunity by regulating the development of medullary thymic epithelial cells
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29 September 2017
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Autoimmune polyendocrinopathy syndrome type 1 (APS1) and AIRE gene: new views on molecular basis of autoimmunity
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29 September 2017
Modifier loci condition autoimmunity provoked by Aire deficiency
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PubMed Central
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Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels
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PubMed Central
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29 September 2017
Regulating self-tolerance by deregulating gene expression
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PubMed Central
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29 September 2017
Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity.
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Lymphotoxin pathway directs thymic Aire expression
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Thymic medullary epithelial cell differentiation, thymocyte emigration, and the control of autoimmunity require lympho-epithelial cross talk via LTbetaR.
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29 September 2017
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PubMed Central
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29 September 2017
Medullary but not cortical thymic epithelial cells present soluble antigens to helper T cells
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PubMed Central
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29 September 2017
Studies on T cell maturation on defined thymic stromal cell populations in vitro
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2 June 2018
Aire-dependent alterations in medullary thymic epithelium indicate a role for Aire in thymic epithelial differentiation.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Peripheral antigen display by lymph node stroma promotes T cell tolerance to intestinal self
1 reference
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PubMed Central
reference URL
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27 November 2018
Onset of promiscuous gene expression in murine fetal thymus organ culture.
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PubMed Central
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27 November 2018
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells.
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PubMed Central
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27 November 2018
Development of functional thymic epithelial cells occurs independently of lymphostromal interactions.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Haploinsufficiency of the cardiac transcription factor Nkx2-5 variably affects the expression of putative target genes.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1994210
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27 November 2018
Essential role of IkappaB kinase alpha in thymic organogenesis required for the establishment of self-tolerance
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17599412
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17599412
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17599412
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Genetic and tissue-specific variation in the expression of a closely linked murine multigene family on chromosome 15 that encodes salivary and lacrimal proteins
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17599412
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17599412
retrieved
12 December 2020
based on heuristic
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Identifiers
DOI
10.1016/J.MOLIMM.2007.05.014
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
389171
OpenCitations bibliographic resource ID
389171
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
389171
PMCID
1994210
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
389171
PubMed ID
17599412
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
389171
ResearchGate publication ID
6238961
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