(Q28213185)

4

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Sylvie Lesage

object named as

Sylvie Lesage

2

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Adrian Liston

object named as

Adrian Liston

1

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author name string

Judith Wilson

3

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Christopher C Goodnow

Ablation of "tolerance" and induction of diabetes by virus infection in viral antigen transgenic mice

5

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language of work or name

English

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publication date

April 2003

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published in

Nature Immunology

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volume

4

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issue

4

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page(s)

350-4

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cites work

1 reference

7 January 2021

Following a diabetogenic T cell from genesis through pathogenesis

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7 January 2021

Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein.

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A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity

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High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

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Fulminant spontaneous autoimmunity of the central nervous system in mice transgenic for the myelin proteolipid protein-specific T cell receptor

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7 January 2021

Phenotypic and functional analysis of CD8(+) T cells undergoing peripheral deletion in response to cross-presentation of self-antigen.

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7 January 2021

Tolerance induction to self antigens by peripheral dendritic cells

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7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

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7 January 2021

Evidence for a thymus-dependent form of tolerance that is not based on elimination or anergy of reactive T cells

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7 January 2021

Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen

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7 January 2021

Deletion of high-avidity T cells by thymic epithelium

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7 January 2021

A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis.

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7 January 2021

CD4 T cell tolerance to human C-reactive protein, an inducible serum protein, is mediated by medullary thymic epithelium

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7 January 2021

T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus

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Promiscuous gene expression and central T-cell tolerance: more than meets the eye.

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Clinical review 93: Autoimmune polyglandular syndrome type 1.

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Positional cloning of the APECED gene

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An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

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7 January 2021

The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein

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7 January 2021

Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein

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Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

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Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.

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7 January 2021

Localization of the APECED protein in distinct nuclear structures

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Projection of an immunological self shadow within the thymus by the aire protein

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Failure to censor forbidden clones of CD4 T cells in autoimmune diabetes.

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7 January 2021

Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.

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Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen.

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Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells.

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The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens

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Role for CCR7 ligands in the emigration of newly generated T lymphocytes from the neonatal thymus

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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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Some quantitative aspects of T-cell repertoire selection: the requirement for regulatory T cells

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Regulatory T cells: key controllers of immunologic self-tolerance

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RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse

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T lymphocyte tolerance: from thymic deletion to peripheral control mechanisms

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7 January 2021

Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity

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7 January 2021

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7 January 2021

Regulatory function of in vivo anergized CD4(+) T cells

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Anergic T cells inhibit the antigen-presenting function of dendritic cells

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7 January 2021

Anergic T cells actively suppress T cell responses via the antigen-presenting cell

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7 January 2021

Anergic T cells as suppressor cells in vitro

1 reference

7 January 2021

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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7 January 2021

Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

1 reference

7 January 2021

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

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7 January 2021

A defect in central tolerance in NOD mice

1 reference

7 January 2021

Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells.

1 reference

7 January 2021

High frequency of autoreactive myelin proteolipid protein-specific T cells in the periphery of naive mice: mechanisms of selection of the self-reactive repertoire

1 reference

7 January 2021

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

1 reference

7 January 2021