(Q14907847)

English

Frataxin

mammalian protein found in Mus musculus

frataxin, mitochondrial
Fxn
Friedreich ataxia
uniprot:O35943

In more languages

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Frataxin/CyaY superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35943

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35943

Frataxin conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

metal ion binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

oxidoreductase activity

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

ferroxidase activity

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

ferrous iron binding

determination method

3 references

ferric iron binding

determination method

4 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

iron chaperone activity

determination method

3 references

2 iron, 2 sulfur cluster binding

determination method

3 references

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

determination method

3 references

determination method

7 references

1 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

determination method

8 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

A mitochondrial protein compendium elucidates complex I disease biology

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

biological process

negative regulation of multicellular organism growth

determination method

1 reference

14 February 2019

Reduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

iron ion homeostasis

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

mitochondrion organization

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

embryo development ending in birth or egg hatching

determination method

1 reference

14 February 2019

Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

heme biosynthetic process

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

iron-sulfur cluster assembly

determination method

3 references

1 January 2018

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

determination method

2 references

negative regulation of organ growth

determination method

1 reference

14 February 2019

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

cellular iron ion homeostasis

determination method

4 references

1 January 2018

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

1 January 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

iron incorporation into metallo-sulfur cluster

determination method

3 references

cellular response to oxidative stress

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35943&geneProductId=UniProtKB:O35943

determination method

cellular iron ion homeostasis

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

mitochondrion organization

determination method

3 references

14 February 2019

Hypertension, cardiac hypertrophy, and sudden death in mice lacking natriuretic peptide receptor A

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

iron-sulfur cluster assembly

determination method

5 references

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

positive regulation of axon extension

determination method

1 reference

14 February 2019

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35943

determination method

Frataxin conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35943

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000080081

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000080081

ENSMUSP00000117047

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000117047

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q14907847&oldid=2023072167"