(Q14911575)

TGFβ superfamily receptor

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

activin types I and II receptor domain, protein family

1 reference

GS domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Serine/threonine-protein kinase, active site, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

signaling receptor binding

1 reference

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

protein serine/threonine kinase activity

3 references

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta receptor activity, type I

transforming growth factor beta binding

4 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

transmembrane receptor protein serine/threonine kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta-activated receptor activity

5 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

12 references

14 February 2019

SNX25 regulates TGF-β signaling by enhancing the receptor degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

RLP, a novel Ras-like protein, is an immediate-early transforming growth factor-beta (TGF-beta) target gene that negatively regulates transcriptional activity induced by TGF-beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

LRG1 promotes angiogenesis by modulating endothelial TGF-β signalling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Stem cell antigen-1 enhances tumorigenicity by disruption of growth differentiation factor-10 (GDF10)-dependent TGF-beta signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

ShcA Protects against Epithelial-Mesenchymal Transition through Compartmentalized Inhibition of TGF-β-Induced Smad Activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

TGF-beta signaling specifies axons during brain development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Dlg5 interacts with the TGF-β receptor and promotes its degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

VE-cadherin is a critical endothelial regulator of TGF-beta signalling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

ubiquitin protein ligase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

protein-containing complex binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

protein heterodimerization activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta-activated receptor activity

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Galectin-9-CD44 interaction enhances stability and function of adaptive regulatory T cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta receptor activity, type I

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

growth factor binding

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta binding

3 references

1 reference

11 October 2018

SNX25 regulates TGF-β signaling by enhancing the receptor degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

bicellular tight junction

3 references

3 references

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Cholesterol suppresses cellular TGF-beta responsiveness: implications in atherogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

intracellular anatomical structure

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

basolateral plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

apical plasma membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

protein-containing complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

integral component of plasma membrane

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

3 references

activin receptor complex

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

3 references

3 references

1 reference

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

2 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

activin receptor signaling pathway

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

skeletal system morphogenesis

1 reference

14 February 2019

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

post-embryonic development

1 reference

14 February 2019

Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

negative regulation of chondrocyte differentiation

1 reference

14 February 2019

Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

regulation of epithelial to mesenchymal transition

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

parathyroid gland development

1 reference

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transmembrane receptor protein serine/threonine kinase signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

collagen fibril organization

1 reference

14 February 2019

Altered primordial germ cell migration in the absence of transforming growth factor beta signaling via ALK5

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

cellular response to transforming growth factor beta stimulus

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

skeletal system development

1 reference

14 February 2019

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

roof of mouth development

negative regulation of apoptotic process

endothelial cell activation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

anterior/posterior pattern specification

1 reference

14 February 2019

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

in utero embryonic development

3 references

14 February 2019

Tgf-beta3-induced palatal fusion is mediated by Alk-5/Smad pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

intracellular signal transduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

endothelial cell migration

1 reference

14 February 2019

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

mesenchymal cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of filopodium assembly

1 reference

14 February 2019

Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development

male gonad development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

lens development in camera-type eye

1 reference

14 February 2019

Requirement for TGFbeta receptor signaling during terminal lens fiber differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

embryonic cranial skeleton morphogenesis

1 reference

14 February 2019

Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

pharyngeal system development

1 reference

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of endothelial cell proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

Identification of two distinct functions for TGF-beta in early mouse development

blastocyst development

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of transcription, DNA-templated

3 references

1 reference

14 February 2019

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

regulation of protein binding

1 reference

14 February 2019

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

negative regulation of endothelial cell proliferation

1 reference

14 February 2019

Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-β in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

cardiac epithelial to mesenchymal transition

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

Transforming growth factor beta 2 promotes the formation of the mouse cochleovestibular ganglion in organ culture

response to cholesterol

3 references

neuron fate commitment

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

proepicardium development

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

regulation of cardiac muscle cell proliferation

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

ventricular septum morphogenesis

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of stress fiber assembly

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta receptor signaling pathway

9 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-β in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

24 April 2018

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q64729&geneProductId=UniProtKB:Q64729

coronary artery morphogenesis

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

ventricular compact myocardium morphogenesis

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

Signaling via the Tgf-beta type I receptor Alk5 in heart development

epicardium morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of tight junction disassembly

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

angiogenesis involved in coronary vascular morphogenesis

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

ventricular trabecula myocardium morphogenesis

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of epithelial to mesenchymal transition

1 reference

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of apoptotic process

1 reference

14 February 2019

Critical roles of miRNA-mediated regulation of TGFβ signalling during mouse cardiogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of gene expression

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

negative regulation of endothelial cell differentiation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

protein autophosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

negative regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

positive regulation of pri-miRNA transcription by RNA polymerase II

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

transforming growth factor beta receptor signaling pathway

9 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Caveolin-2 is a negative regulator of anti-proliferative function and signaling of transforming growth factor-β in endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Signaling via the Tgf-beta type I receptor Alk5 in heart development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

pattern specification process

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q64729

serine/threonine-protein kinase, active site

has part(s)

1 reference

activin types I and II receptor domain

1 reference

protein kinase, ATP binding site

1 reference

GS domain

1 reference

protein kinase domain

1 reference