Wikidata

(Q14913250)

English

SKI proto-oncogene

mammalian protein found in Homo sapiens

  • v-ski avian sarcoma viral oncogene homolog
  • ski oncogene
  • SKI
  • proto-oncogene c-Ski
  • ski oncoprotein
In more languages
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No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
17 references
retrieved
8 April 2019
stated in
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Complex formation between proteins encoded by the ski gene family
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Ski regulates muscle terminal differentiation by transcriptional activation of Myog in a complex with Six1 and Eya3
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Protooncogene Ski cooperates with the chromatin-remodeling factor Satb2 in specifying callosal neurons.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Inhibiting Drivers of Non-mutational Drug Tolerance Is a Salvage Strategy for Targeted Melanoma Therapy
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Ski-binding protein C184M negatively regulates tumor growth factor-beta signaling by sequestering the Smad proteins in the cytoplasm
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Functional proteomics mapping of a human signaling pathway
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Ski is a component of the histone deacetylase complex required for transcriptional repression by Mad and thyroid hormone receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
DACH1 inhibits transforming growth factor-beta signaling through binding Smad4
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IPI
cell component
biological process
negative regulation of transforming growth factor beta receptor signaling pathway
determination method or standard
IBA
IDA
IGI
IMP
5 references
retrieved
8 April 2019
stated in
Nuclear and cytoplasmic c-Ski differently modulate cellular functions
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IMP
retrieved
8 April 2019
stated in
SKI and MEL1 cooperate to inhibit transforming growth factor-beta signal in gastric cancer cells
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IMP
retrieved
8 April 2019
stated in
The protooncogene Ski controls Schwann cell proliferation and myelination
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IGI
retrieved
8 April 2019
stated in
Involvement of the constitutive complex formation of c-Ski/SnoN with Smads in the impaired negative feedback regulation of transforming growth factor beta signaling in scleroderma fibroblasts
GOA
curator
UniProt
UniProt protein ID
P12755
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12755
determination method or standard
IBA
Gene Atlas image
PBB GE SKI 204270 at fs.png
732 × 530; 12 KB
0 references

Identifiers

 
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