(Q14914104)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QUK6

Leucine-rich repeat domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9QUK6

membrane protein

1 reference

inferred from GOA cell component → membrane

Toll/interleukin-1 receptor homology (TIR) domain, protein family

1 reference

Cysteine-rich flanking region, C-terminal domain, protein family

1 reference

Leucine-rich repeat, typical subtype, protein family

1 reference

Leucine-rich repeat, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

12 references

9 August 2016

9 May 2019

CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

WDFY1 mediates TLR3/4 signaling by recruiting TRIF

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Crystal structure of the TLR4-MD-2 complex with bound endotoxin antagonist Eritoran

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

An unusual dimeric structure and assembly for TLR4 regulator RP105–MD-1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

transmembrane signaling receptor activity

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

8 April 2019

lipopolysaccharide binding

4 references

9 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

lipopolysaccharide immune receptor activity

4 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

phosphatidylinositol 3-kinase binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

cell component

membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

1 reference

9 May 2019

integral component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

1 reference

9 May 2019

plasma membrane

3 references

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QUK6&geneProductId=UniProtKB:Q9QUK6

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QUK6&geneProductId=UniProtKB:Q9QUK6

16 September 2017

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9QUK6&geneProductId=UniProtKB:Q9QUK6

lipopolysaccharide receptor complex

ISS

integral component of plasma membrane

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

1 reference

9 May 2019

early endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

1 reference

9 May 2019

plasma membrane

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

membrane raft

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

phagocytic cup

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of JNK cascade

biological process

4 references

9 August 2016

9 May 2019

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

cellular response to mechanical stimulus

2 references

9 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

I-kappaB phosphorylation

4 references

9 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The S100A8-serum amyloid A3-TLR4 paracrine cascade establishes a pre-metastatic phase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of interleukin-6 production

8 references

9 August 2016

9 May 2019

Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of tumor necrosis factor production

7 references

9 August 2016

9 May 2019

The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Cutting edge: heat shock protein 60 is a putative endogenous ligand of the toll-like receptor-4 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

innate immune response

TAS

inflammatory response

1 reference

9 August 2016

negative regulation of interleukin-17 production

3 references

9 August 2016

9 May 2019

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

mast cell activation

3 references

9 August 2016

9 May 2019

Protective roles of mast cells against enterobacterial infection are mediated by Toll-like receptor 4

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

NAS

9 May 2019

Toll-like receptor 4-mediated activation of murine mast cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

toll-like receptor 4 signaling pathway

NAS

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

8 April 2019

positive regulation of interleukin-10 production

3 references

9 August 2016

9 May 2019

MicroRNA-98 negatively regulates IL-10 production and endotoxin tolerance in macrophages after LPS stimulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

immune system process

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

response to lipopolysaccharide

8 references

9 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The role of lipopolysaccharide binding protein in resistance to Salmonella infections in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Cutting edge: functional characterization of the effect of the C3H/HeJ defect in mice that lack an Lpsn gene: in vivo evidence for a dominant negative mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

A point mutation in the IL-12R beta 2 gene underlies the IL-12 unresponsiveness of Lps-defective C57BL/10ScCr mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of chemokine production

4 references

9 August 2016

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

lipopolysaccharide-mediated signaling pathway

4 references

9 August 2016

9 May 2019

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of nitric oxide biosynthetic process

1 reference

9 August 2016

negative regulation of interleukin-6 production

3 references

9 August 2016

9 May 2019

Unexpected regulatory roles of TLR4 and TLR9 in experimental autoimmune encephalomyelitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

MyD88-dependent toll-like receptor signaling pathway

1 reference

9 August 2016

positive regulation of gene expression

1 reference

9 August 2016

defense response to Gram-negative bacterium

1 reference

9 August 2016

positive regulation of I-kappaB kinase/NF-kappaB signaling

4 references

9 August 2016

9 May 2019

The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

macrophage activation

4 references

9 August 2016

9 May 2019

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

detection of lipopolysaccharide

4 references

9 August 2016

9 May 2019

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

cellular response to lipopolysaccharide

1 reference

9 August 2016

signal transduction

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

toll-like receptor signaling pathway

1 reference

9 August 2016

microglial cell activation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

innate immune response-activating signal transduction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

leukotriene metabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

response to oxidative stress

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of gene expression

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

TRIF-dependent toll-like receptor signaling pathway

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of macrophage activation

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of apoptotic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of DNA binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of nitric oxide biosynthetic process

response to ethanol

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

defense response to Gram-negative bacterium

Immune activation of type I IFNs by Listeria monocytogenes occurs independently of TLR4, TLR2, and receptor interacting protein 2 but involves TNFR-associated NF kappa B kinase-binding kinase 1

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

detection of temperature stimulus involved in sensory perception of pain

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

detection of mechanical stimulus involved in sensory perception of pain

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of DNA-binding transcription factor activity

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

regulation of sensory perception of pain

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

response to fatty acid

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

cellular response to lipopolysaccharide

8 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

TLR4 signaling in effector CD4+ T cells regulates TCR activation and experimental colitis in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

The toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

9 May 2019

Exploring New Inflammatory Biomarkers and Pathways during LPS-Induced M1 Polarization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

negative regulation of cold-induced thermogenesis

1 reference

9 May 2019

Activation of Toll-like receptor 4 (TLR4) attenuates adaptive thermogenesis via endoplasmic reticulum stress.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

cellular response to oxidised low-density lipoprotein particle stimulus

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of cytokine production involved in inflammatory response

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of oxidative stress-induced neuron death

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

positive regulation of reactive oxygen species biosynthetic process

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

phagocytosis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

MyD88-dependent toll-like receptor signaling pathway

1 reference

9 May 2019

CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUK6

defense response to Gram-negative bacterium

physically interacts with

2 references

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

2770

17 August 2016

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016