(Q28513075)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide (English)

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

0 references

0 references

0 references

1 reference

Tumor necrosis factor

1 reference

Toll-like receptor 9

1 reference

Toll-like receptor 8

1 reference

Thymoma viral proto-oncogene 1

1 reference

RPTOR independent companion of MTOR, complex 2

1 reference

Toll-like receptor 4

1 reference

author

William T Festuccia

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

David M. Sabatini

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

author name string

Philippe Pouliot

2

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Inan Bakan

3

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

Mathieu Laplante

5

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

language of work or name

English

0 references

publication date

16 April 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

volume

9

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

page(s)

e95432

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

issue

4

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

14 March 2020

copyright license

start time

16 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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1 reference

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19 March 2017

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B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K

19 March 2017

1 reference

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19 March 2017

1 reference

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Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages

19 March 2017

1 reference

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19 March 2017

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The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

19 March 2017

1 reference

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mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

19 March 2017

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19 March 2017

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AKT/PKB signaling: navigating downstream

19 March 2017

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Inflammation and metabolic disorders

19 March 2017

1 reference

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Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity

19 March 2017

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

19 March 2017

1 reference

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Insulin attenuates the systemic inflammatory response in endotoxemic rats

19 March 2017

1 reference

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Obesity is associated with macrophage accumulation in adipose tissue

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Alternative activation of macrophages

19 March 2017

1 reference

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The phosphoinositide 3-kinase pathway

19 March 2017

1 reference

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

19 March 2017

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

19 March 2017

1 reference

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Macrophages, inflammation, and insulin resistance

7 April 2017

1 reference

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Protective and pathogenic functions of macrophage subsets

7 April 2017

1 reference

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Adipokines in inflammation and metabolic disease

7 April 2017

1 reference

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The nuts and bolts of AGC protein kinases

7 April 2017

1 reference

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TLR4 links innate immunity and fatty acid-induced insulin resistance

7 April 2017

1 reference

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Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling

7 April 2017

1 reference

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Toll-like receptors, signaling adapters and regulation of the pro-inflammatory response by PI3K

29 September 2017

1 reference

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Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization

29 September 2017

1 reference

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Loss of Pdk1-Foxo1 signaling in myeloid cells predisposes to adipose tissue inflammation and insulin resistance.

29 September 2017

1 reference

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Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.

29 September 2017

1 reference

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FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages

29 September 2017

1 reference

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TLR-signaling networks: an integration of adaptor molecules, kinases, and cross-talk.

29 September 2017

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The role of adipose tissue and lipotoxicity in the pathogenesis of type 2 diabetes

29 September 2017

1 reference

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FoxO1 links insulin resistance to proinflammatory cytokine IL-1beta production in macrophages.

29 September 2017

1 reference

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Therapeutic targeting of Toll-like receptors for infectious and inflammatory diseases and cancer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Role of phosphoinositide 3-kinase in innate immunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Osteopontin mediates obesity-induced adipose tissue macrophage infiltration and insulin resistance in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

The role of the ErbB family members in non-small cell lung cancers sensitive to epidermal growth factor receptor kinase inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Role of MyD88 in phosphatidylinositol 3-kinase activation by flagellin/toll-like receptor 5 engagement in colonic epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Obesity-induced inflammatory changes in adipose tissue.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Tumor necrosis factor mediates endotoxic effects in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Re-evaluating AKT regulation: role of TOR complex 2 in tissue growth

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3989321

Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

2 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095432

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095432

Increased infiltration of macrophages in omental adipose tissue is associated with marked hepatic lesions in morbid human obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095432

PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0095432

Timing of insulin therapy affects the inflammatory response in endotoxemic rats

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24740015

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Body temperature in normal and endotoxin-treated mice of different ages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24740015

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0095432

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

2 references

25 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24740015%20AND%20SRC:MED&resulttype=core&format=json