(Q28505138)

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Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages

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scholarly article

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PubMed publication ID

24 January 2017

Phosphoinositide-dependent kinase 1 provides negative feedback inhibition to Toll-like receptor-mediated NF-kappaB activation in macrophages (English)

1 reference

PubMed publication ID

24 January 2017

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toll-like receptor

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3-phosphoinositide dependent protein kinase 1

1 reference

GOA release 2020-03-11

Jens C Brüning

6

object named as

Jens C. Brüning

1 reference

PubMed publication ID

24 January 2017

author name string

Bhagirath Chaurasia

1

1 reference

PubMed publication ID

24 January 2017

Jan Mauer

2

1 reference

PubMed publication ID

24 January 2017

Linda Koch

3

1 reference

PubMed publication ID

24 January 2017

Julia Goldau

4

1 reference

PubMed publication ID

24 January 2017

Anja-Sterner Kock

5

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PubMed publication ID

24 January 2017

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publication date

1 September 2010

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PubMed publication ID

24 January 2017

Molecular and Cellular Biology

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PubMed publication ID

24 January 2017

30

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PubMed publication ID

24 January 2017

17

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PubMed publication ID

24 January 2017

4354–4366

1 reference

PubMed publication ID

24 January 2017

Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation

1 reference

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TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation

1 reference

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Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination

1 reference

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19 March 2017

3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signaling

1 reference

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19 March 2017

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

1 reference

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19 March 2017

De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

19 March 2017

Toll-like receptor signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

19 March 2017

CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members

1 reference

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19 March 2017

IRAK-M is a negative regulator of Toll-like receptor signaling

1 reference

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19 March 2017

Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation

1 reference

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19 March 2017

Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression

1 reference

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Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

1 reference

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

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19 March 2017

Phosphorylation and activation of p70s6k by PDK1

1 reference

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19 March 2017

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

1 reference

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TRAF6 is a signal transducer for interleukin-1

1 reference

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19 March 2017

Inducible phosphorylation of I kappa B alpha is not sufficient for its dissociation from NF-kappa B and is inhibited by protease inhibitors

1 reference

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19 March 2017

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

1 reference

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19 March 2017

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

19 March 2017

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

19 March 2017

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

7 April 2017

The two NF-kappaB activation pathways and their role in innate and adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

7 April 2017

Toll-like receptors and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

7 April 2017

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2937543

7 April 2017

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

1 reference

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7 April 2017

TRAF6 distinctively mediates MyD88- and IRAK-1-induced activation of NF-kappaB.

2 references

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29 September 2017

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12 December 2020

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Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice

1 reference

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29 September 2017

Central insulin action in energy and glucose homeostasis

1 reference

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Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity

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29 September 2017

Enhanced NF-kappaB activation and cellular function in macrophages lacking IkappaB kinase 1 (IKK1).

1 reference

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Molecular mechanism of TNF signaling and beyond

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Toll-like receptor signaling

1 reference

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29 September 2017

PI3K and negative regulation of TLR signaling.

1 reference

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29 September 2017

A new molecular target of insulin action: regulating the pivotal PDK1.

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The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

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1 reference

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How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex

1 reference

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1 reference

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Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

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Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3.

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Endotoxemia in human septic shock

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Identifiers

10.1128/MCB.00069-10

1 reference

PubMed publication ID

24 January 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

24 January 2017

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