(Q48021625)

7 February 2018

review article

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title

Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin (English)

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7 February 2018

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A K Srivastava

1

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7 February 2018

S K Pandey

series ordinal

2

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7 February 2018

publication date

1 May 1998

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7 February 2018

Molecular and Cellular Biochemistry

published in

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7 February 2018

volume

182

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7 February 2018

issue

1-2

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7 February 2018

page(s)

135-141

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7 February 2018

https://scigraph.springernature.com/pub.10.1023/a:1006857527588

exact match

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cites work

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Mechanism of activation of protein kinase B by insulin and IGF-1

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Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and beta-adrenergic agonists in rat epididymal fat cells. Activation of protein kinase B by wortmannin-sensitive and -insensitive mechanisms

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A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

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Regulation of protein phosphatase 1 and 2A activities by insulin during myogenesis in rat skeletal muscle cells in culture.

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Upstream mechanisms of glycogen synthase activation by insulin and insulin-like growth factor-I. Glycogen synthase activation is antagonized by wortmannin or LY294002 but not by rapamycin or by inhibiting p21ras

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Insulin activates protein kinase B, inhibits glycogen synthase kinase-3 and activates glycogen synthase by rapamycin-insensitive pathways in skeletal muscle and adipose tissue

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Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells

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Regulation of both glycogen synthase and PHAS-I by insulin in rat skeletal muscle involves mitogen-activated protein kinase-independent and rapamycin-sensitive pathways

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12 December 2020

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

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12 December 2020

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily

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12 December 2020

The α-isoform of glycogen synthase kinase-3 from rabbit skeletal muscle is inactivated by p70 S6 kinase or MAP kinase-activated protein kinase-1 in vitro

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A reinvestigation of the phosphorylation of rabbit skeletal-muscle glycogen synthase by cyclic-AMP-dependent protein kinase. Identification of the third site of phosphorylation as serine-7

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12 December 2020

Insulin action and the insulin signaling network

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Stimulation of protein phosphatase-1 activity by insulin in rat adipocytes. Evaluation of the role of mitogen-activated protein kinase pathway

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

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Studies with wortmannin suggest a role for phosphatidylinositol 3-kinase in the activation of glycogen synthase and mitogen-activated protein kinase by insulin in rat adipocytes: comparison of insulin and protein kinase C modulators

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12 December 2020

Inactivation of rabbit muscle glycogen synthase by glycogen synthase kinase-3. Dominant role of the phosphorylation of Ser-640 (site-3a).

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12 December 2020

Control of glycogen synthase by hierarchal protein phosphorylation

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12 December 2020

Modular binding domains in signal transduction proteins

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12 December 2020

Signal transduction and protein phosphorylation in the regulation of cellular metabolism by insulin

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12 December 2020

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

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12 December 2020

Analysis of the in vivo phosphorylation state of rabbit skeletal muscle glycogen synthase by fast-atom-bombardment mass spectrometry

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12 December 2020

Identification of multifunctional ATP-citrate lyase kinase as the alpha-isoform of glycogen synthase kinase-3

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12 December 2020

Expression of a dominant-negative Ras mutant does not affect stimulation of glucose uptake and glycogen synthesis by insulin

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12 December 2020

Signalling through the lipid products of phosphoinositide-3-OH kinase

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12 December 2020

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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12 December 2020

Multiple signalling pathways involved in the stimulation of fatty acid and glycogen synthesis by insulin in rat epididymal fat cells.

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

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Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo

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Insulin action in cultured human myoblasts: contribution of different signalling pathways to regulation of glycogen synthesis.

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The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

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12 December 2020

p85alpha gene generates three isoforms of regulatory subunit for phosphatidylinositol 3-kinase (PI 3-Kinase), p50alpha, p55alpha, and p85alpha, with different PI 3-kinase activity elevating responses to insulin

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12 December 2020

Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase

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12 December 2020

Molecular cloning and characterisation of a novel putative protein-serine kinase related to the cAMP-dependent and protein kinase C families

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12 December 2020

Characterization of a rabbit skeletal muscle protein kinase (PC0.7) able to phosphorylate glycogen synthase and phosvitin.

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12 December 2020

Three forms of phosphatase type 1 in Swiss 3T3 fibroblasts. Free catalytic subunit appears to mediate s6 dephosphorylation

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12 December 2020

PTG, a protein phosphatase 1-binding protein with a role in glycogen metabolism

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12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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12 December 2020

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

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12 December 2020

A synthetic inhibitor of the mitogen-activated protein kinase cascade

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12 December 2020

Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.

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12 December 2020

The effect of modulating the glycogen-associated regulatory subunit of protein phosphatase-1 on insulin action in rat skeletal muscle cells

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12 December 2020

Facilitative glucose transporters

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12 December 2020

On target with a new mechanism for the regulation of protein phosphorylation

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12 December 2020

The molecular mechanism by which adrenalin inhibits glycogen synthesis

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12 December 2020

Molecular cloning and characterization of a new member of the RAC protein kinase family: association of the pleckstrin homology domain of three types of RAC protein kinase with protein kinase C subspecies and beta gamma subunits of G proteins

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12 December 2020

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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12 December 2020

Synergistic phosphorylation of rabbit muscle glycogen synthase by cyclic AMP-dependent protein kinase and casein kinase I. Implications for hormonal regulation of glycogen synthase

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12 December 2020

Molecular cloning and expression of glycogen synthase kinase-3/factor A

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12 December 2020

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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12 December 2020

Separation and characterisation of glycogen synthase kinase 3, glycogen synthase kinase 4 and glycogen synthase kinase 5 from rabbit skeletal muscle

1 reference

12 December 2020

Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: insulin activation of type 1 phosphatase

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12 December 2020

Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

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12 December 2020

Multisite and hierarchal protein phosphorylation.

1 reference

12 December 2020

Acute regulation of hepatic protein phosphatases by glucagon, insulin, and glucose

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12 December 2020

Identifiers

DOI

10.1023/A:1006857527588

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7 February 2018

Dimensions Publication ID

1029291330

0 references

1 reference

7 February 2018