(Q15316702)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P37198

animal nuclear pore complex

1 reference

Transporter Classification Database ID

1.I.1.1.3

hierarchical database ID heuristic

2 October 2019

based on heuristic

Nucleoporin, NSP1-like, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

Hsp90 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

chromatin binding

1 reference

8 April 2019

Structure and functional properties of the ubiquitin binding protein p62

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

PTB domain binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

Hsp70 protein binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

protein binding

22 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Nucleophosmin is essential for ribosomal protein L5 nuclear export

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

A new role for nuclear transport factor 2 and Ran: nuclear import of CapG

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

p62 forms a ternary complex with PKCζ and PAR‐4 and antagonizes PAR‐4‐induced PKCζ inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Sequestosome 1/p62 shuttles polyubiquitinated tau for proteasomal degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Systematic Protein-Protein Interaction Analysis Reveals Intersubcomplex Contacts in the Nuclear Pore Complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

The DEAD-box RNA helicase DDX3 associates with export messenger ribonucleoproteins as well as tip-associated protein and participates in translational control

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Next-generation sequencing to generate interactome datasets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

signaling receptor complex adaptor activity

structural constituent of nuclear pore

3 references

phospholipid binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

kinesin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

signaling receptor complex adaptor activity

1 reference

8 April 2019

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

SH2 domain binding

1 reference

8 April 2019

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

ubiquitin binding

1 reference

8 April 2019

p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

thyroid hormone receptor binding

1 reference

8 April 2019

p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

cell component

Flemming body

1 reference

8 April 2019

The actin-capping protein CapG localizes to microtubule-dependent organelles during the cell cycle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

nuclear pore

Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization

7 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

Quantitative regulation of nuclear pore complex proteins by O-GlcNAcylation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

lamellae anulatae

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

nuclear pore central transport channel

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

cytoplasm

The p56(lck)-interacting protein p62 stimulates transcription via the SV40 enhancer

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

centrosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

mitotic spindle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

nuclear envelope

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

protein-containing complex

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

ribonucleoprotein complex

1 reference

8 April 2019

Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

nuclear pore

Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Human nucleoporin p62 and the essential yeast nuclear pore protein NSP1 show sequence homology and a similar domain organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

8 April 2019

Quantitative regulation of nuclear pore complex proteins by O-GlcNAcylation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

host cell

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

biological process

mRNA transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

negative regulation of epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

regulation of Ras protein signal transduction

1 reference

8 April 2019

T cell regulation of p62(dok) (Dok1) association with Crk-L

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

negative regulation of Ras protein signal transduction

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of transcription, DNA-templated

cell surface receptor signaling pathway

The p56(lck)-interacting protein p62 stimulates transcription via the SV40 enhancer

3 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

10 September 2018

Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

regulation of signal transduction

1 reference

8 April 2019

p62, a phosphotyrosine-independent ligand of the SH2 domain of p56lck, belongs to a new class of ubiquitin-binding proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

negative regulation of MAP kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

spermatogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

regulation of protein import into nucleus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

hormone-mediated signaling pathway

1 reference

8 April 2019

p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

protein transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

negative regulation of programmed cell death

nuclear transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

positive regulation of epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

negative regulation of cell population proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

3 references

10 September 2018

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

10 September 2018

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=P37198&geneProductId=UniProtKB:P37198

mRNA export from nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

mitotic metaphase plate congression

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

mitotic centrosome separation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of mitotic nuclear division

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of centriole replication

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

regulation of mitotic spindle organization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

centriole assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of mitotic cytokinetic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of protein localization to centrosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

centrosome cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

mitotic cell cycle

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

protein heterotrimerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

regulation of glycolytic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

transcription, DNA-templated

1 reference

8 April 2019

The p56(lck)-interacting protein p62 stimulates transcription via the SV40 enhancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

tRNA export from nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

cell surface receptor signaling pathway

cell death

1 reference

8 April 2019

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

protein sumoylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

viral transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

negative regulation of apoptotic process

1 reference

8 April 2019

p62 forms a ternary complex with PKCζ and PAR‐4 and antagonizes PAR‐4‐induced PKCζ inhibition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

negative regulation of programmed cell death

1 reference

8 April 2019

The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

The interaction of p62 with RIP links the atypical PKCs to NF-kappaB activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

positive regulation of transcription, DNA-templated

1 reference

8 April 2019

p62, A TFIIH subunit, directly interacts with thyroid hormone receptor and enhances T3-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

regulation of gene silencing by miRNA

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

intracellular transport of virus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

regulation of cellular response to heat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37198

1 reference

8 April 2019

physically interacts with

Viroporin 3a

Affinity Capture-MS

1 reference

https://thebiogrid.org/news/227

19 April 2020

A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

BioGRID

has part(s)

Nucleoporin, NSP1-like, C-terminal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P37198

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

English

Transporter Classification Database ID

1.I.1.1.3

2 references

Transporter Classification database

13 March 2020

Transporter Classification database