(Q24291680)

regulation of Ras protein signal transduction

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

4

B E Bierer

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author name string

M P Martelli

series ordinal

1

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J Boomer

series ordinal

2

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M Bu

series ordinal

3

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language of work or name

English

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publication date

7 December 2001

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published in

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volume

276

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issue

49

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page(s)

45654-61

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cites work

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Physical association of the cytoplasmic domain of CD2 with the tyrosine kinases p56lck and p59fyn

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The SH3 domain of p56lck binds to proline-rich sequences in the cytoplasmic domain of CD2

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CD2 signaling in T cells involves tyrosine phosphorylation and activation of the Tec family kinase, EMT/ITK/TSK.

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The involvement of the proto-oncogene p120 c-Cbl and ZAP-70 in CD2-mediated T cell activation

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Signal transduction by the CD2 antigen in T cells and natural killer cells: requirement for expression of a functional T cell receptor or binding of antibody Fc to the Fc receptor, Fc gamma RIIIA (CD16)

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CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells

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Identification of a signaling complex involving CD2, zeta chain and p59fyn in T lymphocytes

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CD2-mediated signaling in T cells lacking the zeta-chain-specific immune receptor tyrosine-based activation (ITAM) motif

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CD2-mediated adhesion facilitates T lymphocyte antigen recognition function

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Separable portions of the CD2 cytoplasmic domain involved in signaling and ligand avidity regulation

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Differential T-cell antigen receptor signaling mediated by the Src family kinases Lck and Fyn.

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LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway

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p62dok negatively regulates CD2 signaling in Jurkat cells

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Interactions of p62(dok) with p210(bcr-abl) and Bcr-Abl-associated proteins.

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SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL

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Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

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Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

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Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein

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Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating protein

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p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells

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Identification of the Abl- and rasGAP-associated 62 kDa protein as a docking protein, Dok

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Differential effects of B cell receptor and B cell receptor-FcgammaRIIB1 engagement on docking of Csk to GTPase-activating protein (GAP)-associated p62

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The RasGAP-binding protein p62dok is a mediator of inhibitory FcgammaRIIB signals in B cells

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Mediation by the protein-tyrosine kinase Tec of signaling between the B cell antigen receptor and Dok-1.

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Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

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SHP-1 regulation of p62(DOK) tyrosine phosphorylation in macrophages

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Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity

21 January 2018

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Domain-dependent function of the rasGAP-binding protein p62Dok in cell signaling

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Rap1 signalling: adhering to new models

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Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

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Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors

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https://api.crossref.org/works/10.1074%2FJBC.M105777200

Role of Crk oncogene product in physiologic signaling.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M105777200

Activation of the Rap1 GTPase by the B cell antigen receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Physiological signals and oncogenesis mediated through Crk family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

The adapter protein Crkl links Cbl to C3G after integrin ligation and enhances cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Nck-interacting Ste20 kinase couples Eph receptors to c-Jun N-terminal kinase and integrin activation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M105777200

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

CMS: an adapter molecule involved in cytoskeletal rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A distinct cytoplasmic domain of CD2 regulates ligand avidity and T-cell responsiveness to antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Interaction between human CD2 and CD58 involves the major beta sheet surface of each of their respective adhesion domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Recruitment of Activated p56lckon Endosomes of CD2-triggered T Cells, Colocalization with ZAP-70

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Transmembrane signalling via the T11-dependent pathway of human T cell activation. Evidence for the involvement of 1,2-diacylglycerol and inositol phosphates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Differential interaction of the CD2 extracellular and intracellular domains with the tyrosine phosphatase CD45 and the zeta chain of the TCR/CD3/zeta complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Coordinate regulation of T cell activation by CD2 and CD28

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A p56lck-independent Pathway of CD2 Signaling Involves Jun Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

A critical role for p59fyn in CD2-based signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Priming of CD2-induced p62Dok tyrosine phosphorylation by CD3 in Jurkat T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200

ZAP-70 is required for calcium mobilization but is dispensable for mitogen-activated protein kinase (MAPK) superfamily activation induced via CD2 in human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105777200