(Q15320351)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

3 references

14 February 2019

Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

extracellular matrix structural constituent

IPI

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

3 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

31 January 2018

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

4 references

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

2 references

4 references

1 January 2018

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

protein-containing complex

HDA

1 reference

14 February 2019

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

collagen-containing extracellular matrix

IDA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

3 references

14 February 2019

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

growth plate cartilage development

HDA

biological process

4 references

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

2 references

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

extracellular matrix organization

IEA

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

skeletal system development

IEA

1 reference

14 February 2019

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

chondrocyte development

2 references

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

Interaction between cartilage oligomeric matrix protein and extracellular matrix protein 1 mediates endochondral bone growth.

endochondral bone growth

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

growth plate cartilage development

5 references

1 January 2018

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

response to unfolded protein

IBA

1 reference

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

multicellular organism aging

1 reference

14 February 2019

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

vascular associated smooth muscle contraction

1 reference

14 February 2019

Cartilage oligomeric matrix protein prevents vascular aging and vascular smooth muscle cells senescence.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

collagen fibril organization

3 references

14 February 2019

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

regulation of bone mineralization

1 reference

14 February 2019

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

BMP signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

multicellular organism growth

2 references

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

chondrocyte proliferation

3 references

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

COMP-assisted collagen secretion--a novel intracellular function required for fibrosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Shift of Macrophage Phenotype Due to Cartilage Oligomeric Matrix Protein Deficiency Drives Atherosclerotic Calcification.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

A mouse model offers novel insights into the myopathy and tendinopathy often associated with pseudoachondroplasia and multiple epiphyseal dysplasia

musculoskeletal movement

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

Mild myopathy is associated with COMP but not MATN3 mutations in mouse models of genetic skeletal diseases

neuromuscular process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

Analysis of the cartilage proteome from three different mouse models of genetic skeletal diseases reveals common and discrete disease signatures.

cartilage development

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

4 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

A novel form of chondrocyte stress is triggered by a COMP mutation causing pseudoachondroplasia.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

vascular associated smooth muscle cell development

1 reference

14 February 2019

Cartilage oligomeric matrix protein inhibits vascular smooth muscle calcification by interacting with bone morphogenetic protein-2.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

1 reference

14 February 2019

Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

negative regulation of hemostasis

1 reference

14 February 2019

Cartilage oligomeric matrix protein is a natural inhibitor of thrombin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9R0G6

positive regulation of chondrocyte proliferation

1 reference

1 January 2018

Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9R0G6&geneProductId=UniProtKB:Q9R0G6

positive regulation of chondrocyte proliferation

IBA

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016

1 reference

10 August 2016