(Q15425261)

Platycodin D (English)

7 October 2016

chemical formula

C₅₇H₉₂O₂₈

1 reference

Platycodin D (English)

19 November 2016

canonical SMILES

CC1C(C(C(C(O1)OC2C(C(COC2OC(=O)C34CCC(CC3C5=CCC6C(C5(CC4O)C)(CCC7C6(CC(C(C7(CO)CO)OC8C(C(C(C(O8)CO)O)O)O)O)C)C)(C)C)O)O)O)O)OC9C(C(C(CO9)O)OC1C(C(CO1)(CO)O)O)O

1 reference

Platycodin D (English)

19 November 2016

isomeric SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@H](CO[C@H]2OC(=O)[C@]34CCC(C[C@H]3C5=CC[C@H]6[C@]([C@@]5(C[C@H]4O)C)(CC[C@@H]7[C@@]6(C[C@@H]([C@@H](C7(CO)CO)O[C@H]8[C@@H]([C@H]([C@@H]([C@H](O8)CO)O)O)O)O)C)C)(C)C)O)O)O)O)O[C@H]9[C@@H]([C@H]([C@@H](CO9)O)O[C@H]1[C@@H]([C@](CO1)(CO)O)O)O

1 reference

Platycodin D (English)

19 November 2016

found in taxon

Platycodon grandiflorum

18 references

In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase

Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay

Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells.

A comparative study on commercial, botanical gardens and wild samples of the roots of Platycodon grandiflorum by HPLC analysis

New triterpenoid saponins from the roots of Platycodon grandiflorum

Saponins from roots of Platycodon grandiflorum. Part 2. Isolation and structure of new triterpene glycosides

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters

Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats

Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice

Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells

Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells

Platycodin D induces apoptosis in MCF-7 human breast cancer cells

[Evaluations of saponin properties of HPLC analysis of Platycodon grandiflorum A.DC]

Eight New Oleanane-Type Triterpenoid Saponins from Platycodon Root

Saponins from roots of Platycodon grandiflorum. Part 2. Isolation and structure of new triterpene glycosides

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

Ameliorating effect of balloon flower saponin on the ethanol-induced memory impairment in mice.

Platycodon grandiflorus

18 references

Ameliorating effect of balloon flower saponin on the ethanol-induced memory impairment in mice.

In vitro inhibitory effect of triterpenoidal saponins from Platycodi Radix on pancreatic lipase

Determination of the kinetic properties of platycodin D for the inhibition of pancreatic lipase using a 1,2-diglyceride-based colorimetric assay

Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells.

A comparative study on commercial, botanical gardens and wild samples of the roots of Platycodon grandiflorum by HPLC analysis

New triterpenoid saponins from the roots of Platycodon grandiflorum

Saponins from roots of Platycodon grandiflorum. Part 2. Isolation and structure of new triterpene glycosides

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

Platycodin D and D3 increase airway mucin release in vivo and in vitro in rats and hamsters

Stimulative effects of saponin from kikyo-to, a Japanese herbal medicine, on pancreatic exocrine secretion of conscious rats

Saponins from platycodi radix ameliorate high fat diet-induced obesity in mice

Antiproliferative effects of saponins from the roots of Platycodon grandiflorum on cultured human tumor cells

Implication of intracellular ROS formation, caspase-3 activation and Egr-1 induction in platycodon D-induced apoptosis of U937 human leukemia cells

Platycodin D induces apoptosis in MCF-7 human breast cancer cells

[Evaluations of saponin properties of HPLC analysis of Platycodon grandiflorum A.DC]

Eight New Oleanane-Type Triterpenoid Saponins from Platycodon Root

Saponins from roots of Platycodon grandiflorum. Part 2. Isolation and structure of new triterpene glycosides

Inhibition of prostaglandin E2 production by platycodin D isolated from the root of Platycodon grandiflorum.

Identifiers

InChI

InChI=1S/C57H92O28/c1-23-40(81-45-39(72)41(28(64)18-76-45)82-49-43(73)56(75,21-61)22-78-49)36(69)38(71)46(79-23)83-42-33(66)27(63)17-77-48(42)85-50(74)57-12-11-51(2,3)13-25(57)24-7-8-30-52(4)14-26(62)44(84-47-37(70)35(68)34(67)29(16-58)80-47)55(19-59,20-60)31(52)9-10-53(30,5)54(24,6)15-32(57)65/h7,23,25-49,58-73,75H,8-22H2,1-6H3/t23-,25-,26-,27-,28+,29+,30+,31+,32+,33-,34+,35-,36-,37+,38+,39+,40-,41-,42+,43-,44-,45-,46-,47-,48-,49-,52+,53+,54+,56+,57+/m0/s1

0 references

InChIKey

CYBWUNOAQPMRBA-NDTOZIJESA-N

2 references

Platycodin D (English)

19 November 2016

ChEBI release 2020-09-01

2 references

platycodin D (English)

CYBWUNOAQPMRBA-NDTOZIJESA-N

7 October 2016

InChIKey

9 April 2021

https://commonchemistry.cas.org/detail?cas_rn=58479-68-8

1 reference

3-O-[(2S,3R,4R)-3,4-Dihydroxy-4-(hydroxymethyl)tetrahydro-2-furanyl]-beta-D-xylopyranosyl-(1->4)-6-deoxy-alpha-L-mannopyranosyl-(1->2)-1-O-[(2beta,3beta,16alpha)-3-(beta-D-glucopyranosyloxy)-2,16,23,2 (English)

7 October 2016

2 references