(Q21096383)

EF-hand domain pair

1 reference

EF-hand domain, protein family

1 reference

Calponin homology domain, protein family

1 reference

EF-hand, Ca insensitive, protein family

1 reference

Actinin-type actin-binding domain, conserved site, protein family

1 reference

Spectrin repeat, protein family

1 reference

EF-Hand 1, calcium-binding site, protein family

1 reference

Spectrin/alpha-actinin, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

3 references

8 April 2019

Structural dynamics of alpha-actinin-vinculin interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

3 references

8 April 2019

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Modulation of alpha-actinin levels affects cell motility and confers tumorigenicity on 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

IDA

actin filament binding

3 references

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

14 references

8 April 2019

Identification of a novel member of the chloride intracellular channel gene family (CLIC5) that associates with the actin cytoskeleton of placental microvilli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

ADIP, a novel Afadin- and alpha-actinin-binding protein localized at cell-cell adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

A human interactome in three quantitative dimensions organized by stoichiometries and abundances

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Towards a proteome-scale map of the human protein–protein interaction network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Direct interaction between α‐actinin and hepatitis C virus NS5B

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Phosphorylated alpha-actinin and protein-tyrosine phosphatase 1B coregulate the disassembly of the focal adhesion kinase x Src complex and promote cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle?

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

nuclear receptor coactivator activity

IPI

1 reference

8 April 2019

Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

double-stranded RNA binding

IDA

1 reference

8 April 2019

Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

structural constituent of postsynapse

3 references

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

ACTN1 mutations cause congenital macrothrombocytopenia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Postsynaptic recruitment of Dendrin depends on both dendritic mRNA transport and synaptic anchoring

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

Alpha-actinin and vinculin in human neutrophils: reorganization during adhesion and relation to the actin network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

3 references

17 October 2017

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

17 October 2017

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

17 October 2017

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

extracellular exosome

4 references

17 October 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

17 October 2017

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

17 October 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

17 October 2017

Protein profile of exosomes from trabecular meshwork cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

platelet alpha granule lumen

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

17 October 2017

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

1 reference

8 April 2019

Human colostrum: identification of minor proteins in the aqueous phase by proteomics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

intracellular anatomical structure

HDA

1 reference

1 January 2018

α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

3 references

8 April 2019

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Dynamics of alpha-actinin in focal adhesions and stress fibers visualized with alpha-actinin-green fluorescent protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

HDA

extracellular exosome

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Large-scale proteomics and phosphoproteomics of urinary exosomes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

Protein profile of exosomes from trabecular meshwork cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

8 April 2019

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

regulation of apoptotic process

HDA

glutamatergic synapse

3 references

1 reference

8 April 2019

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

actin filament organization

NAS

1 reference

8 April 2019

ACTN1 mutations cause congenital macrothrombocytopenia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

actin filament network formation

1 reference

8 April 2019

A missense mutation in the alpha-actinin 1 gene (ACTN1) is the cause of autosomal dominant macrothrombocytopenia in a large French family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

platelet degranulation

1 reference

8 April 2019

1 reference

8 April 2019

ACTN1 mutations cause congenital macrothrombocytopenia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

Disruption of alpha-actinin-integrin interactions at focal adhesions renders osteoblasts susceptible to apoptosis

focal adhesion assembly

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

actin crosslink formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

ACTN1 mutations cause congenital macrothrombocytopenia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

1 reference

8 April 2019

A missense mutation in the alpha-actinin 1 gene (ACTN1) is the cause of autosomal dominant macrothrombocytopenia in a large French family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

regulation of nucleic acid-templated transcription

1 reference

17 October 2017

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P12814&geneProductId=UniProtKB:P12814

postsynapse organization

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

positive regulation of nucleic acid-templated transcription

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P12814

has part(s)

Spectrin/alpha-actinin

1 reference

Spectrin repeat

1 reference

EF-hand domain

1 reference

EF-hand, Ca insensitive

1 reference

Calponin homology domain

1 reference

Actinin-type actin-binding domain, conserved site

1 reference

EF-hand 1, calcium-binding site

1 reference

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016

1 reference

5 August 2016