(Q24305523)

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Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors

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scholarly article

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Familial focal segmental glomerulosclerosis (FSGS)-linked α-actinin 4 (ACTN4) protein mutants lose ability to activate transcription by nuclear hormone receptors (English)

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alpha-actinin binding

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GOA release 2020-03-11

focal segmental glomerulosclerosis

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based on heuristic

inferred from title

Peter Mathieson

8

object named as

Peter W Mathieson

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7

object named as

Moin A Saleem

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author name string

Simran Khurana

1

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Sharmistha Chakraborty

2

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Minh Lam

3

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Yu Liu

4

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Yu-Ting Su

5

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Xuan Zhao

6

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Leslie A Bruggeman

9

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Hung-Ying Kao

10

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language of work or name

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publication date

6 April 2012

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Journal of Biological Chemistry

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287

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12027-35

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15

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Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Actinin-4, a novel actin-bundling protein associated with cell motility and cancer invasion

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Structure of the alpha-actinin rod: molecular basis for cross-linking of actin filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

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19 March 2017

Structure and specificity of nuclear receptor-coactivator interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

The nuclear receptor superfamily: the second decade

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Overview of nomenclature of nuclear receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

FSGS-associated alpha-actinin-4 (K256E) impairs cytoskeletal dynamics in podocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Proteinuria and the expression of the podocyte slit diaphragm protein, nephrin, in diabetic nephropathy: effects of angiotensin converting enzyme inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

The spectrin repeat: a structural platform for cytoskeletal protein assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Nuclear receptor minireview series

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

19 March 2017

Regulation of gene expression by retinoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Role of the retinoic acid receptor-α in HIV-associated nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The actin-binding protein, actinin alpha 4 (ACTN4), is a nuclear receptor coactivator that promotes proliferation of MCF-7 breast cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Dose- and time-dependent glucocorticoid receptor signaling in podocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The glomerulus--a view from the outside--the podocyte

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Molecular make-up of the glomerular filtration barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Proteinuria: an enzymatic disease of the podocyte?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Molecular genetic analysis of podocyte genes in focal segmental glomerulosclerosis--a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Alpha-actinin structure and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The podocyte in health and disease: insights from the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Recovery and maintenance of nephrin expression in cultured podocytes and identification of HGF as a repressor of nephrin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Direct effects of dexamethasone on human podocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Screening and identification of substances that regulate nephrin gene expression using engineered reporter podocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The effect of dexamethasone on defective nephrin transport caused by ER stress: a potential mechanism for the therapeutic action of glucocorticoids in the acquired glomerular diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Nuclear hormone receptor coregulator: role in hormone action, metabolism, growth, and development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Retinoid X receptor alpha (RXRalpha) helix 12 plays an inhibitory role in the recruitment of the p160 co-activators by unliganded RXRalpha/retinoic acid receptor alpha heterodimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Alpha-actinin revisited: a fresh look at an old player

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The coactivator LXXLL nuclear receptor recognition motif.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Nuclear receptors and the control of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Cell biology of the glomerular podocyte

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

A conditionally immortalized human podocyte cell line demonstrating nephrin and podocin expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Rearrangements of the cytoskeleton and cell contacts induce process formation during differentiation of conditionally immortalized mouse podocyte cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

Cell-extracellular matrix interactions can regulate the switch between growth and differentiation in rat hepatocytes: reciprocal expression of C/EBP alpha and immediate-early growth response transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

27 September 2017

The subtypes of peroxisome proliferator-activated receptors expressed by human podocytes and their role in decreasing podocyte injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3320949

30 May 2018

Retinoids regulate the repairing process of the podocytes in puromycin aminonucleoside-induced nephrotic rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

Induction of nephrin gene expression by selective cooperation of the retinoic acid receptor and the vitamin D receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

Mutational and Biological Analysis of alpha-actinin-4 in focal segmental glomerulosclerosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

Transcriptional Regulation of Nephrin Gene by Peroxisome Proliferator-Activated Receptor- Agonist: Molecular Mechanism of the Antiproteinuric Effect of Pioglitazone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

α-Actinin-4 Is Required for Normal Podocyte Adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.345421

21 January 2018

Preparation and study of isolated glomeruli

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma agonist is protective in podocyte injury-associated sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha-actinin 4 potentiates myocyte enhancer factor-2 transcription activity by antagonizing histone deacetylase 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms underlying nucleocytoplasmic shuttling of actinin-4

1 reference

https://pubmed.ncbi.nlm.nih.gov/22351778

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M112.345421

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