(Q21102539)

English

DEP domain containing 5, GATOR1 subcomplex subunit

mammalian protein found in Homo sapiens

DEPDC5
DEP domain containing 5
GATOR complex protein DEPDC5
DEP domain-containing protein 5

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Statements

1 reference

13 November 2019

Winged helix DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75140

Winged helix-like DNA-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75140

Vacuolar membrane-associated protein Iml1

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75140

DEP domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

protein-containing complex binding

determination method

IDA

GTPase activator activity

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

1 reference

26 September 2017

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

26 September 2017

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

26 September 2017

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

4 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

9 May 2019

Integral and associated lysosomal membrane proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

determination method

HDA

Cul3-RING ubiquitin ligase complex

1 reference

9 May 2019

KLHL22 activates amino-acid-dependent mTORC1 signalling to promote tumorigenesis and ageing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

determination method

IDA

biological process

negative regulation of TOR signaling

1 reference

26 September 2017

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

determination method

IMP

cellular response to amino acid starvation

1 reference

26 September 2017

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

determination method

IMP

intracellular signal transduction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

determination method

IEA

positive regulation of GTPase activity

1 reference

9 May 2019

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75140

determination method

IEA

regulation of autophagy

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O75140&geneProductId=UniProtKB:O75140

1 reference

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/O75140

Identifiers

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(Q21102539)

DEP domain containing 5, GATOR1 subcomplex subunit

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