(Q21106978)

Protein kinase-like domain superfamily

1 reference

SH2 domain superfamily

2 references

http://www.ebi.ac.uk/interpro/protein/H3BU69

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

SH2 domain, protein family

1 reference

CSK-like, SH2 domain, protein family

1 reference

SH3 domain, protein family

1 reference

Protein kinase domain, protein family

1 reference

Protein kinase, ATP binding site, protein family

1 reference

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

Tyrosine-protein kinase, active site, protein family

1 reference

2 references

13 November 2019

17 September 2016

2 references

13 November 2019

21 March 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein kinase activity

1 reference

8 April 2019

protein kinase A catalytic subunit binding

1 reference

8 April 2019

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein C-terminus binding

1 reference

8 April 2019

Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

10 references

8 April 2019

SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Inhibition of T cell activation by cyclic adenosine 5'-monophosphate requires lipid raft targeting of protein kinase A type I by the A-kinase anchoring protein ezrin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Large-scale structural analysis of the classical human protein tyrosine phosphatome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Structural basis for the recognition of c-Src by its inactivator Csk

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

C-terminal Src kinase associates with ligand-stimulated insulin-like growth factor-I receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

identical protein binding

IPI

1 reference

8 April 2019

The tyrosine kinase Csk dimerizes through Its SH3 domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein tyrosine kinase activity

IPI

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

cyl encodes a putative cytoplasmic tyrosine kinase lacking the conserved tyrosine autophosphorylation site (Y416src)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein phosphatase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

proline-rich region binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

signaling receptor binding

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

2 references

non-membrane spanning protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein tyrosine kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:H3BU69

3 references

26 September 2017

Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

extrinsic component of cytoplasmic side of plasma membrane

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

4 references

8 April 2019

Association of inhibitory tyrosine protein kinase p50csk with protein tyrosine phosphatase PEP in T cells and other hemopoietic cells

HUGO Gene Nomenclature Committee

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

Large-scale proteomics and phosphoproteomics of urinary exosomes

extracellular exosome

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

adaptive immune response

1 reference

8 April 2019

positive regulation of MAP kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

epidermal growth factor receptor signaling pathway

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

negative regulation of phagocytosis

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

transmembrane receptor protein tyrosine kinase signaling pathway

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

negative regulation of low-density lipoprotein particle clearance

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

immune system process

1 reference

8 April 2019

negative regulation of interleukin-6 production

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

oligodendrocyte differentiation

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

negative regulation of Golgi to plasma membrane protein transport

1 reference

8 April 2019

The Lyn kinase C-lobe mediates Golgi export of Lyn through conformation-dependent ACSL3 association

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

regulation of cytokine production

IDA

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

protein phosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

cellular response to peptide hormone stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

regulation of cell population proliferation

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

peptidyl-tyrosine autophosphorylation

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

negative regulation of ERK1 and ERK2 cascade

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

protein autophosphorylation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

innate immune response

1 reference

26 September 2017

T cell receptor signaling pathway

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

negative regulation of cell population proliferation

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

negative regulation of bone resorption

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

negative regulation of kinase activity

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41240

central nervous system development

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41240&geneProductId=UniProtKB:P41240

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:H3BU69

protein phosphorylation

1 reference

8 April 2019

tyrosine-protein kinase, active site

has part(s)

1 reference

SH3 domain

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference

tyrosine-protein kinase, catalytic domain

1 reference

SH2 domain

2 references

http://www.ebi.ac.uk/interpro/protein/H3BU69

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

CSK-like, SH2 domain

1 reference

D08.811.913.696.620.682.725.800.158

Identifiers

MeSH descriptor ID

D000081247

subject named as

CSK Tyrosine-Protein Kinase

0 references

MeSH tree code

0 references

D12.776.476.568.800.158

0 references

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

21 March 2016

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference