(Q21107386)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15328

Putative uncharacterized transport proteins

1 reference

Transporter Classification Database ID

9.B.92.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

Folate receptor-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

1 reference

8 April 2019

Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

folic acid receptor activity

IC

1 reference

26 September 2017

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

folic acid transmembrane transporter activity

IC

UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor

3 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

folic acid binding

Lack of association between mutations in the folate receptor-alpha gene and spina bifida

9 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Structural basis for molecular recognition of folic acid by folate receptors

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

folic acid binding

Lack of association between mutations in the folate receptor-alpha gene and spina bifida

10 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Cloning of a tumor-associated antigen: MOv18 and MOv19 antibodies recognize a folate-binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Structural basis for molecular recognition of folic acid by folate receptors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

signaling receptor activity

IBA

IBA

folic acid receptor activity

UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

anchored component of external side of plasma membrane

IC

cell component

2 references

extracellular region

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

brush border

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

clathrin-coated vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

ER to Golgi transport vesicle membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

anchored component of membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

Golgi membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

nucleus

1 reference

8 April 2019

Nuclear localization of folate receptor alpha: a new role as a transcription factor

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

integral component of plasma membrane

1 reference

26 September 2017

Interaction of folate receptor with signaling molecules lyn and G(alpha)(i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

membrane

Interaction of folate receptor with signaling molecules lyn and G(alpha)(i-3) in detergent-resistant complexes from the ovary carcinoma cell line IGROV1

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Molecular cloning and characterization of the human folate-binding protein cDNA from placenta and malignant tissue culture (KB) cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

cell surface

1 reference

26 September 2017

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

brush border membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

basolateral plasma membrane

1 reference

8 April 2019

Expression and differential polarization of the reduced-folate transporter-1 and the folate receptor alpha in mammalian retinal pigment epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

cytoplasmic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

endosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

endoplasmic reticulum-Golgi intermediate compartment membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

anchored component of plasma membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

extracellular exosome

3 references

26 September 2017

Proteomic analysis of podocyte exosome-enriched fraction from normal human urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

transport vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

cell surface

HDA

1 reference

8 April 2019

Quantitative proteomics identifies a Dab2/integrin module regulating cell migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

anchored component of external side of plasma membrane

HDA

Complementary DNA for the folate binding protein correctly predicts anchoring to the membrane by glycosyl-phosphatidylinositol

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

IBA

extracellular exosome

receptor-mediated endocytosis

HDA

biological process

1 reference

8 April 2019

Lack of association between mutations in the folate receptor-alpha gene and spina bifida

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

cellular response to folic acid

1 reference

8 April 2019

Translational upregulation of folate receptors is mediated by homocysteine via RNA-heterogeneous nuclear ribonucleoprotein E1 interactions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

COPII vesicle coating

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

endoplasmic reticulum to Golgi vesicle-mediated transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

folic acid metabolic process

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

response to axon injury

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

folic acid transport

Lack of association between mutations in the folate receptor-alpha gene and spina bifida

4 references

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

UMSCC38 cells amplified at 11q13 for the folate receptor synthesize a mutant nonfunctional folate receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

26 September 2017

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

transport

http://www.ebi.ac.uk/QuickGO/annotations?protein=P15328&geneProductId=UniProtKB:P15328

1 reference

26 September 2017

folic acid transport

IMP

folate import across plasma membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15328

1 reference

8 April 2019

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P15328

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

Transporter Classification Database ID

English

9.B.92.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database