(Q24312144)

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Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

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Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients (English)

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Folate receptor beta

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GOA release 2020-03-11

Folate receptor alpha

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GOA release 2020-03-11

methotrexate binding

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GOA release 2020-03-11

rheumatoid arthritis

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based on heuristic

inferred from title

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9

object named as

Paul P Tak

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author name string

Joost W van der Heijden

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Ruud Oerlemans

2

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Ben A C Dijkmans

3

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Huiling Qi

4

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Conny J van der Laken

5

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Willem F Lems

6

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Ann L Jackman

7

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Maarten C Kraan

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Manohar Ratnam

10

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Gerrit Jansen

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language of work or name

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publication date

January 2009

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Arthritis & Rheumatology

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60

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12-21

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1

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Differential regulation of folate receptor isoforms in normal and malignant tissues in vivo and in established cell lines. Physiologic and clinical implications

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7 January 2021

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Selective expression of folate receptor beta and its possible role in methotrexate transport in synovial macrophages from patients with rheumatoid arthritis

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https://api.crossref.org/works/10.1002%2FART.24219

7 January 2021

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Modulation of inflammation and metalloproteinase expression in synovial tissue by leflunomide and methotrexate in patients with active rheumatoid arthritis. Findings in a prospective, randomized, double-blind, parallel-design clinical trial in thirt

1 reference

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COBRA combination therapy in patients with early rheumatoid arthritis: long-term structural benefits of a brief intervention

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Folate-targeted imaging of activated macrophages in rats with adjuvant-induced arthritis.

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7 January 2021

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Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment

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7 January 2021

based on heuristic

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Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis

1 reference

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7 January 2021

based on heuristic

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Toward a better understanding of methotrexate

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7 January 2021

based on heuristic

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Effectiveness of anti-folate receptor beta antibody conjugated with truncated Pseudomonas exotoxin in the targeting of rheumatoid arthritis synovial macrophages

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Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial

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7 January 2021

based on heuristic

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Pharmacogenomic and metabolic biomarkers in the folate pathway and their association with methotrexate effects during dosage escalation in rheumatoid arthritis.

1 reference

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7 January 2021

based on heuristic

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A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis

1 reference

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7 January 2021

based on heuristic

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Folate receptor type beta is a neutrophilic lineage marker and is differentially expressed in myeloid leukemia

1 reference

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based on heuristic

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AG2034: a novel inhibitor of glycinamide ribonucleotide formyltransferase

1 reference

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Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo

1 reference

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The folate receptor: what does it promise in tissue-targeted therapeutics?

1 reference

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7 January 2021

based on heuristic

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Molecular basis of antifolate resistance

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From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

1 reference

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7 January 2021

based on heuristic

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Differential stereospecificities and affinities of folate receptor isoforms for folate compounds and antifolates

1 reference

https://api.crossref.org/works/10.1002%2FART.24219

7 January 2021

based on heuristic

inferred from DOI database lookup

Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy

1 reference

https://api.crossref.org/works/10.1002%2FART.24219

7 January 2021

based on heuristic

inferred from DOI database lookup

Antifolates targeted specifically to the folate receptor

1 reference

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7 January 2021

based on heuristic

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Folate receptor-mediated targeting of therapeutic and imaging agents to activated macrophages in rheumatoid arthritis.

1 reference

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7 January 2021

based on heuristic

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Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption

1 reference

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7 January 2021

based on heuristic

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New therapies for treatment of rheumatoid arthritis

1 reference

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7 January 2021

based on heuristic

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Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

1 reference

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7 January 2021

based on heuristic

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The synthesis and thymidylate synthase inhibitory activity of L-gamma-L-linked dipeptide and L-gamma-amide analogues of 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583)

1 reference

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7 January 2021

based on heuristic

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Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523).

1 reference

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7 January 2021

based on heuristic

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Drug Insight: resistance to methotrexate and other disease-modifying antirheumatic drugs--from bench to bedside

1 reference

https://api.crossref.org/works/10.1002%2FART.24219

7 January 2021

based on heuristic

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Therapeutic strategies for rheumatoid arthritis

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7 January 2021

based on heuristic

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Endocytosis of GPI-linked membrane folate receptor-alpha

1 reference

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7 January 2021

based on heuristic

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Ultra-sensitive FISH using peroxidase-mediated deposition of biotin- or fluorochrome tyramides.

1 reference

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7 January 2021

based on heuristic

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A new monoclonal antibody (3A5) that recognises a fixative resistant epitope on tissue macrophages and monocytes

1 reference

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BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors

1 reference

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7 January 2021

based on heuristic

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Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates

1 reference

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7 January 2021

based on heuristic

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Reliability of computerized image analysis for the evaluation of serial synovial biopsies in randomized controlled trials in rheumatoid arthritis

1 reference

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1 reference

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based on heuristic

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10.1002/ART.24219

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