Wikidata

(Q21110095)

English

ERCC excision repair 1, endonuclease non-catalytic subunit

mammalian protein found in Homo sapiens

  • excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
  • DNA excision repair protein ERCC-1
  • excision repair cross-complementation group 1
  • ERCC1
  • ERCC1 protein, human
In more languages

Statements

molecular function
protein binding
determination method
IPI
17 references
retrieved
8 April 2019
stated in
Formation of a ternary complex by human XPA, ERCC1, and ERCC4(XPF) excision repair proteins
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Reconstitution of human excision nuclease with recombinant XPF-ERCC1 complex
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Purification and characterization of the XPF-ERCC1 complex of human DNA repair excision nuclease
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells
GOA
curator
UniProt
UniProt protein ID
P07992
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
A novel cytoplasmic GTPase XAB1 interacts with DNA repair protein XPA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Recognition of helical kinks by xeroderma pigmentosum group A protein triggers DNA excision repair
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
retrieved
8 April 2019
stated in
Human XPF controls TRF2 and telomere length maintenance through distinctive mechanisms
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07992
determination method
IPI
cell component
biological process
Commons category
DNA excision repair protein ERCC-1
0 references

Identifiers

MeSH descriptor ID
C071447
subject named as
ERCC1 protein, human
0 references
 
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