Wikidata

(Q21110097)

English

integrin subunit alpha 5

mammalian protein found in Homo sapiens

  • CD49 antigen-like family member E
  • fibronectin receptor, alpha polypeptide
  • integrin alpha-F
  • VLA-5
  • integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
  • very late activation protein 5, alpha subunit
  • fibronectin receptor subunit alpha
  • integrin alpha-5
  • fibronectin receptor, alpha subunit
  • ITGA5
  • ITGA5/SLC9B1 fusion
  • Integrin alpha5
In more languages

Statements

molecular function
protein binding
determination method
IPI
14 references
retrieved
8 April 2019
stated in
Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta.
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Cell adhesion to fibrillin-1 molecules and microfibrils is mediated by alpha 5 beta 1 and alpha v beta 3 integrins
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Cartilage oligomeric matrix protein/thrombospondin 5 supports chondrocyte attachment through interaction with integrins
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Identification of novel integrin binding partners for calcium and integrin binding protein 1 (CIB1): structural and thermodynamic basis of CIB1 promiscuity
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
CCN3 (NOV) Is a Novel Angiogenic Regulator of the CCN Protein Family
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Basic amino-acid side chains regulate transmembrane integrin signalling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
SHARPIN is an endogenous inhibitor of β1-integrin activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Ganglioside GM3 Inhibits Matrix Metalloproteinase-9 Activation and Disrupts Its Association with Integrin
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Murine lipid phosphate phosphohydrolase-3 acts as a cell-associated integrin ligand
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
retrieved
8 April 2019
stated in
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IPI
cell component
cell surface
determination method
IDA
IEA
7 references
retrieved
17 October 2017
stated in
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IEA
retrieved
17 October 2017
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IEA
retrieved
17 October 2017
stated in
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
17 October 2017
stated in
Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
17 October 2017
stated in
Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
17 October 2017
stated in
Quantitative proteomics identifies a Dab2/integrin module regulating cell migration
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
17 October 2017
stated in
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P08648&geneProductId=UniProtKB:P08648
determination method
IDA
focal adhesion
determination method
HDA
IDA
IEA
5 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IEA
retrieved
8 April 2019
stated in
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
The WD40-domain containing protein CORO2B is specifically enriched in glomerular podocytes and regulates the ventral actin cytoskeleton.
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
HDA
cell surface
determination method
HDA
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IEA
retrieved
8 April 2019
stated in
Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
IDA
retrieved
8 April 2019
stated in
Quantitative proteomics identifies a Dab2/integrin module regulating cell migration
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
HDA
retrieved
8 April 2019
stated in
Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance
GOA
curator
UniProt
UniProt protein ID
P08648
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08648
determination method
HDA
biological process

Identifiers

MeSH descriptor ID
D039482
subject named as
Integrin alpha5
0 references
Freebase ID
/m/03cw4bp
0 references
 
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