(Q21114222)

http://www.ebi.ac.uk/interpro/protein/Q13573

SKI-interacting protein SKIP, SNW domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

transcription corepressor activity

1 reference

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

transcription coactivator activity

3 references

8 April 2019

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

24 references

8 April 2019

CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The product of an oculopharyngeal muscular dystrophy gene, poly(A)-binding protein 2, interacts with SKIP and stimulates muscle-specific gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Dynamic protein-protein interaction wiring of the human spliceosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The crystal structure of PPIL1 bound to cyclosporine A suggests a binding mode for a linear epitope of the SKIP protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Solution structure of human peptidyl prolyl isomerase-like protein 1 and insights into its interaction with SKIP

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

CHES1/FOXN3 interacts with Ski-interacting protein and acts as a transcriptional repressor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Regulation of cyclin D1 RNA stability by SNIP1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

retinoic acid receptor binding

IPI

1 reference

8 April 2019

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

vitamin D receptor binding

1 reference

8 April 2019

Interactions of SKIP/NCoA-62, TFIIB, and retinoid X receptor with vitamin D receptor helix H10 residues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

26 September 2017

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13573&geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

A large intrinsically disordered region in SKIP and its disorder-order transition induced by PPIL1 binding revealed by NMR

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

androgen receptor binding

IPI

1 reference

8 April 2019

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

catalytic step 2 spliceosome

HDA

cell component

1 reference

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

cyclin/CDK positive transcription elongation factor complex

1 reference

8 April 2019

A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

3 references

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The Ski oncoprotein interacts with Skip, the human homolog of Drosophila Bx42

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The death domain-associated protein modulates activity of the transcription co-factor Skip/NcoA62

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

post-mRNA release spliceosomal complex

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13573&geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

Ski-interacting protein (SKIP) interacts with androgen receptor in the nucleus and modulates androgen-dependent transcription.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

U2-type catalytic step 2 spliceosome

1 reference

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

biological process

Notch signaling pathway

1 reference

8 April 2019

cellular response to retinoic acid

TAS

1 reference

8 April 2019

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

positive regulation of transforming growth factor beta receptor signaling pathway

1 reference

8 April 2019

Ski-interacting protein interacts with Smad proteins to augment transforming growth factor-beta-dependent transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

1 reference

8 April 2019

SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

regulation of transcription, DNA-templated

IMP

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13573&geneProductId=UniProtKB:Q13573

positive regulation of mRNA splicing, via spliceosome

1 reference

8 April 2019

Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

regulation of retinoic acid receptor signaling pathway

IMP

1 reference

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Isolation and characterization of a novel coactivator protein, NCoA-62, involved in vitamin D-mediated transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

regulation of vitamin D receptor signaling pathway

1 reference

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

positive regulation of neurogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

retinoic acid receptor signaling pathway

ISS

1 reference

8 April 2019

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

positive regulation of histone H3-K4 methylation

1 reference

8 April 2019

SKIP interacts with c-Myc and Menin to promote HIV-1 Tat transactivation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

positive regulation of vitamin D receptor signaling pathway

transcription initiation from RNA polymerase II promoter

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

negative regulation of transcription, DNA-templated

positive regulation by host of viral transcription

positive regulation of transcription by RNA polymerase II

IMP

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Reciprocal roles of SIRT1 and SKIP in the regulation of RAR activity: implication in the retinoic acid-induced neuronal differentiation of P19 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

transcription, DNA-templated

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13573&geneProductId=UniProtKB:Q13573

mRNA splicing, via spliceosome

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

The human Ski-interacting protein functionally substitutes for the yeast PRP45 gene

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Cryo-EM structure of a human spliceosome activated for step 2 of splicing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

8 April 2019

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

generation of catalytic spliceosome for second transesterification step

IC

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13573&geneProductId=UniProtKB:Q13573

positive regulation of transcription of Notch receptor target

IBA

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

positive regulation of Notch signaling pathway

TAS

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13573

SKI-interacting protein SKIP, SNW domain

TAS

has part(s)

1 reference

stated in

InterPro Release 71.0