(Q21114499)

English

Fem-1 homolog B

mammalian protein found in Homo sapiens

FEM1-beta
protein fem-1 homolog B
FEM1B
fem-1-like in apoptotic pathway protein alpha
F1A-alpha
FEM-1-like death receptor binding protein
fem-1-like death receptor-binding protein alpha

In more languages

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Statements

1 reference

13 November 2019

Ankyrin repeat-containing domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UK73

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

death receptor binding

5 references

8 April 2019

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IPI

ubiquitin-protein transferase activity

1 reference

8 April 2019

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IDA

biological process

regulation of extrinsic apoptotic signaling pathway via death domain receptors

1 reference

8 April 2019

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IMP

regulation of DNA damage checkpoint

1 reference

8 April 2019

Human FEM1B is required for Rad9 recruitment and CHK1 activation in response to replication stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IMP

branching involved in prostate gland morphogenesis

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IEA

regulation of ubiquitin-protein transferase activity

1 reference

8 April 2019

VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IMP

epithelial cell maturation

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IEA

epithelial cell maturation involved in prostate gland development

1 reference

8 April 2019

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

IEA

post-translational protein modification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UK73

determination method

TAS

has part(s)

ankyrin repeat-containing domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UK73

ankyrin repeat

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9UK73

Identifiers

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

(Q21114499)

Fem-1 homolog B

Statements

Identifiers

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