(Q24291692)

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The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis

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11 November 2019

The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis (English)

1 reference

Europe PubMed Central

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11 November 2019

apoptotic process

0 references

Caenorhabditis elegans

0 references

Protein phosphatase, Mg2+/Mn2+ dependent 1A

1 reference

GOA release 2020-03-11

Protein phosphatase, Mg2+/Mn2+ dependent 1F

1 reference

GOA release 2020-03-11

intrinsic apoptotic signaling pathway

1 reference

GOA release 2020-03-11

Sex-determination protein fem-3 CELE_C01F6.4

1 reference

GOA release 2020-03-11

Protein phosphatase fem-2 CELE_T19C3.8

1 reference

GOA release 2020-03-11

Sex-determining protein fem-1 CELE_F35D6.1

1 reference

GOA release 2020-03-11

Shing Leng Chan

2

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11 November 2019

4

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11 November 2019

author name string

Tan KM

1

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11 November 2019

Tan KO

3

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11 November 2019

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14 September 2001

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11 November 2019

Journal of Biological Chemistry

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11 November 2019

276

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11 November 2019

44193-44202

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11 November 2019

47

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11 November 2019

Genetics of programmed cell death in C. elegans: past, present and future.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Sex determination in humans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The evolutionary dynamics of sex determination.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Sex and the single worm: sex determination in the nematode C. elegans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

A sex-determining gene, fem-1, required for both male and hermaphrodite development in Caenorhabditis elegans.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The C. elegans sex-determining gene fem-2 encodes a putative protein phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Caenorhabditis elegans sex-determining protein FEM-2 is a protein phosphatase that promotes male development and interacts directly with FEM-3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The Caenorhabditis elegans sex determination protein FEM-1 is a CED-3 substrate that associates with CED-4 and mediates apoptosis in mammalian cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Post-transcriptional regulation of sex determination in Caenorhabditis elegans: widespread expression of the sex-determining gene fem-1 in both sexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Mammalian protein serine/threonine phosphatase 2C: cDNA cloning and comparative analysis of amino acid sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Molecular cloning of Ca2+/calmodulin-dependent protein kinase phosphatase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Regulation of the activities of multifunctional Ca2+/calmodulin-dependent protein kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

CaM-kinases: modulators of synaptic plasticity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The Ca-calmodulin-dependent protein kinase cascade

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

A novel protein phosphatase that dephosphorylates and regulates Ca2+/calmodulin-dependent protein kinase II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Regulation of multifunctional Ca2+/calmodulin-dependent protein kinases by Ca2+/calmodulin-dependent protein kinase phosphatase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Prediction of the coding sequences of unidentified human genes. I. The coding sequences of 40 new genes (KIAA0001-KIAA0040) deduced by analysis of randomly sampled cDNA clones from human immature myeloid cell line KG-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The cloning expression and tissue distribution of human PP2Cbeta

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

PP2C gamma: a human protein phosphatase with a unique acidic domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The structure and regulation of protein phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Mutational analysis of protein phosphatase 2C involved in abscisic acid signal transduction in higher plants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Effect of cerebral ischemia on calcium/calmodulin-dependent protein kinase II activity and phosphorylation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Calcium/calmodulin-dependent protein kinase inhibition potentiates thapsigargin-mediated cell death in SH-SY5Y human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Calcium/calmodulin-dependent protein kinase type IV (CaMKIV) inhibits apoptosis induced by potassium deprivation in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Ca(2+)/Calmodulin-dependent protein kinase cascade in Caenorhabditis elegans. Implication in transcriptional activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Rapid sequence evolution of the mammalian sex-determining gene SRY.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Rapid evolution of the sex determining locus in Old World mice and rats

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Male development of chromosomally female mice transgenic for Sry.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Evidence for evolutionary conservation of sex-determining genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Conservation of a sex-determining gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Death cycle and Swiss army knives

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

21 January 2018

Specification of male development in Caenorhabditis elegans: the fem genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

7 January 2021

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Cell Death in Development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

7 January 2021

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inferred from DOI database lookup

Subcellular distribution and autophosphorylation of calcium/calmodulin-dependent protein kinase II-α in rat hippocampus in a model of ischemic tolerance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

7 January 2021

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A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

7 January 2021

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Calmodulin-dependent protein kinase II mediates signal transduction in apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105880200

7 January 2021

based on heuristic

inferred from DOI database lookup

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