(Q22010738)

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F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis

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F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis (English)

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apoptotic process

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Caenorhabditis elegans

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Fem-1 homolog B

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GOA release 2020-03-11

regulation of extrinsic apoptotic signaling pathway via death domain receptors

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GOA release 2020-03-11

author name string

S L Chan

1

author given names

S L

author last names

Chan

1 reference

7 February 2023

K O Tan

2

author given names

K O

author last names

Tan

1 reference

7 February 2023

L Zhang

3

author given names

L

author last names

Zhang

1 reference

7 February 2023

K S Yee

4

author given names

K S

author last names

Yee

1 reference

7 February 2023

F Ronca

5

author given names

F

author last names

Ronca

1 reference

7 February 2023

M Y Chan

6

author given names

M Y

author last names

Chan

1 reference

7 February 2023

V C Yu

7

author given names

V C

author last names

Yu

1 reference

7 February 2023

language of work or name

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publication date

5 November 1999

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Journal of Biological Chemistry

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274

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32461-8

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45

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The Fas death factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Genetics of programmed cell death in C. elegans: past, present and future.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The C. elegans protein EGL-1 is required for programmed cell death and interacts with the Bcl-2-like protein CED-9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Caspases: intracellular signaling by proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Cell death induction by receptors of the TNF family: towards a molecular understanding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Death receptors: signaling and modulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

A novel domain within the 55 kd TNF receptor signals cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

A novel protein that interacts with the death domain of Fas/APO1 contains a sequence motif related to the death domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

RAIDD is a new 'death' adaptor molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The product of fem-1, a nematode sex-determining gene, contains a motif found in cell cycle control proteins and receptors for cell-cell interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

A Fas-associated protein factor, FAF1, potentiates Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The ubiquitin-homology protein, DAP-1, associates with tumor necrosis factor receptor (p60) death domain and induces apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Isolation and characterization of a novel member of the neural zinc finger factor/myelin transcription factor family with transcriptional repression activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Gene identification using the yeast two-hybrid system.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

RXR beta: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

1-(5-Isoquinolinesulfonyl)-2-methylpiperazine induces apoptosis in human neuroblastoma cells, SH-SY5Y, through a p53-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The murine fem1 gene family: homologs of the Caenorhabditis elegans sex-determination protein FEM-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Modulation of cell death by Bcl-XL through caspase interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Double identity for proteins of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Hundreds of ankyrin-like repeats in functionally diverse proteins: mobile modules that cross phyla horizontally?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Sex determination compared in Drosophila and Caenorhabditis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Molecular genetics of sex determination in C. elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The embryonic cell lineage of the nematode Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Post-transcriptional regulation of sex determination in Caenorhabditis elegans: widespread expression of the sex-determining gene fem-1 in both sexes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Evidence for evolutionary conservation of sex-determining genes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

The nuclear hormone receptor SEX-1 is an X-chromosome signal that determines nematode sex.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Programmed cell death in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Proteases to die for

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Self-association of the Death Domains of the p55 Tumor Necrosis Factor (TNF) Receptor and Fas/APO1 Prompts Signaling for TNF and Fas/APO1 Effects

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Retinoic acid confers resistance to p53-dependent apoptosis in SH-SY5Y neuroblastoma cells by modulating nuclear import of p53

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

A novel BH3-like domain in BID is required for intramolecular interaction and autoinhibition of pro-apoptotic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.45.32461

21 January 2018

Identifiers

10.1074/JBC.274.45.32461

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