(Q21115486)

SH3-like domain superfamily

1 reference

AH/BAR domain superfamily

1 reference

Amphiphysin 2, SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

BAR domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

13 references

1 January 2018

Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Identification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arrays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Hepatitis C virus infection protein network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

The central proline rich region of POB1/REPS2 plays a regulatory role in epidermal growth factor receptor endocytosis by binding to 14-3-3 and SH3 domain-containing proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Bin2, a functionally nonredundant member of the BAR adaptor gene family

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity

IPI

RNA polymerase binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

identical protein binding

IPI

1 reference

1 January 2018

The myotubularin-amphiphysin 2 complex in membrane tubulation and centronuclear myopathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton

IPI

actin filament binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

5 references

1 January 2018

Roles of tau protein in health and disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

26 September 2017

The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00499&geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00499&geneProductId=UniProtKB:O00499

1 reference

1 January 2018

The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Amphiphysin II (SH3P9; BIN1), a member of the amphiphysin/Rvs family, is concentrated in the cortical cytomatrix of axon initial segments and nodes of ranvier in brain and around T tubules in skeletal muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

2 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

4 references

1 January 2018

Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00499&geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

regulation of endocytosis

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

regulation of neuron differentiation

1 reference

1 January 2018

Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

26 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00499&geneProductId=UniProtKB:O00499

positive regulation of astrocyte differentiation

1 reference

1 January 2018

Induction of apoptosis and differentiation in neuroblastoma and astrocytoma cells by the overexpression of Bin1, a novel Myc interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

multicellular organism development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

muscle cell differentiation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

positive regulation of apoptotic process

1 reference

1 January 2018

The membrane-tubulating potential of amphiphysin 2/BIN1 is dependent on the microtubule-binding cytoplasmic linker protein 170 (CLIP-170)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

cell population proliferation

1 reference

26 September 2017

BIN1 is a novel MYC-interacting protein with features of a tumour suppressor

http://www.ebi.ac.uk/QuickGO/annotations?protein=O00499&geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

1 January 2018

Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

membrane organization

1 reference

1 January 2018

3 references

1 January 2018

Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

cytoskeleton organization

1 reference

1 January 2018

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

endosome to lysosome transport

TAS

1 reference

1 January 2018

BIN1 regulates BACE1 intracellular trafficking and amyloid-β production.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

T-tubule organization

3 references

1 January 2018

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 January 2018

Mutations in BIN1 associated with centronuclear myopathy disrupt membrane remodeling by affecting protein density and oligomerization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O00499

1 reference

SH3 domain

1 reference

Amphiphysin 2, SH3 domain

1 reference

Identifiers

MeSH descriptor ID

C101410

subject named as

BIN1 protein, human

0 references

1 reference

30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

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30 May 2020

1 reference

30 May 2020

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30 May 2020

1 reference

30 May 2020

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30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

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9 August 2016

inferred by common MeSH mappings on source and on Wikidata

1 reference