Wikidata

(Q21115725)

English

Eukaryotic translation initiation factor 4 gamma 1

mammalian protein found in Homo sapiens

  • p220
  • eukaryotic translation initiation factor 4 gamma 1
  • EIF4-gamma
  • eucaryotic translation initiation factor 4G
  • eIF-4-gamma 1
  • EIF4G1
In more languages

Statements

molecular function
protein binding
determination method
IPI
31 references
retrieved
8 April 2019
stated in
Post-transcriptional regulation of thioredoxin by the stress inducible heterogenous ribonucleoprotein A18.
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
The RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNA
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
AUF1 contributes to Cryptochrome1 mRNA degradation and rhythmic translation
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Embryonic poly(A)-binding protein stimulates translation in germ cells
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Multiple portions of poly(A)-binding protein stimulate translation in vivo
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Interaction of eIF4G with poly(A)-binding protein stimulates translation and is critical for Xenopus oocyte maturation
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Up-regulation of PDCD4 in senescent human diploid fibroblasts
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Cell stress modulates the function of splicing regulatory protein RBM4 in translation control
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Two zebrafish eIF4E family members are differentially expressed and functionally divergent
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Human INT6/eIF3e is required for nonsense-mediated mRNA decay
GOA
curator
UniProt
UniProt protein ID
Q04637
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Human eukaryotic initiation factor 4G (eIF4G) protein binds to eIF3c, -d, and -e to promote mRNA recruitment to the ribosome
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
eIF4GI facilitates the MicroRNA-mediated gene silencing
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Structural Analysis of the DAP5 MIF4G Domain and Its Interaction with eIF4A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
DEAD-box protein DDX3 associates with eIF4F to promote translation of selected mRNAs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Crystal structure of the yeast eIF4A-eIF4G complex: an RNA-helicase controlled by protein-protein interactions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Assembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Recognition of eIF4G by rotavirus NSP3 reveals a basis for mRNA circularization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
eIF4E-bound mRNPs are substrates for nonsense-mediated mRNA decay in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Translational repression precedes and is required for ZAP-mediated mRNA decay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Reversing chemoresistance by small molecule inhibition of the translation initiation complex eIF4F
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Cell stress modulates the function of splicing regulatory protein RBM4 in translation control
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
p97/DAP5 is a ribosome-associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
eIF4G is required for the pioneer round of translation in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Characterization of mammalian eIF4E-family members
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Proteomics of herpes simplex virus infected cell protein 27: association with translation initiation factors
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
retrieved
8 April 2019
stated in
Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q04637
determination method
IPI
cell component
biological process

Identifiers

Ensembl protein ID
 
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