Wikidata

(Q21116768)

English

Activating transcription factor 2

mammalian protein found in Homo sapiens

  • CREB-2
  • cAMP-responsive element-binding protein 2
  • cAMP responsive element binding protein 2, formerly
  • cAMP response element-binding protein CRE-BP1
  • ATF2
  • cAMP-dependent transcription factor ATF-2
  • cyclic AMP-dependent transcription factor ATF-2
  • HB16
  • activating transcription factor 2 splice variant ATF2-var2
  • histone acetyltransferase ATF2
  • cyclic AMP-responsive element-binding protein 2
In more languages

Statements

molecular function
protein binding
determination method
IPI
15 references
retrieved
8 April 2019
stated in
Characterization of functional domains of an embryonic stem cell coactivator UTF1 which are conserved and essential for potentiation of ATF-2 activity
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
ATM-dependent phosphorylation of ATF2 is required for the DNA damage response
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Regulation of TIP60 by ATF2 modulates ATM activation
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Isolation and characterization of a novel member of the gene family encoding the cAMP response element-binding protein CRE-BP1
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Mutual regulation of c-Jun and ATF2 by transcriptional activation and subcellular localization
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
In situ proximity ligation detection of c-Jun/AP-1 dimers reveals increased levels of c-Jun/Fra1 complexes in aggressive breast cancer cell lines in vitro and in vivo
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
JNK-ATF-2 inhibits thrombomodulin (TM) expression by recruiting histone deacetylase4 (HDAC4) and forming a transcriptional repression complex in the TM promoter
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
The palmitoyl acyltransferase HIP14 shares a high proportion of interactors with huntingtin: implications for a role in the pathogenesis of Huntington's disease
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
A comprehensive resource of interacting protein regions for refining human transcription factor networks
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
The N-terminal transactivation domain of ATF2 is a target for the co-operative activation of the c-jun promoter by p300 and 12S E1A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
retrieved
8 April 2019
stated in
Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IPI
cell component
nucleus
determination method
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IEA
retrieved
8 April 2019
stated in
PKCε promotes oncogenic functions of ATF2 in the nucleus while blocking its apoptotic function at mitochondria
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IDA
retrieved
8 April 2019
stated in
Regulation of TIP60 by ATF2 modulates ATM activation
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IDA
retrieved
8 April 2019
stated in
Hyperosmotic stress-induced ATF-2 activation through Polo-like kinase 3 in human corneal epithelial cells
GOA
curator
UniProt
UniProt protein ID
P15336
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IDA
retrieved
8 April 2019
stated in
CREB proteins function as positive regulators of the translocated bcl-2 allele in t(14;18) lymphomas
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IDA
retrieved
8 April 2019
stated in
cJun modulates Ggamma-globin gene expression via an upstream cAMP response element
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15336
determination method
IDA
biological process

Identifiers

MeSH descriptor ID
D051698
subject named as
Activating Transcription Factor 2
0 references
Ensembl protein ID
 
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