Wikidata

(Q21116814)

English

DNA damage inducible transcript 3

mammalian protein found in Homo sapiens

  • growth arrest and DNA damage-inducible protein GADD153
  • DNA damage-inducible transcript 3 protein
  • CHOP-10
  • CHOP
  • alternative DDIT3 protein
  • c/EBP-homologous protein 10
  • CCAAT/enhancer-binding protein homologous protein
  • DDIT3
  • DDIT-3
  • C/EBP zeta
  • C/EBP-homologous protein
In more languages
default for all languages
No label defined

No description defined

Statements

molecular function
protein binding
determination method or standard
IPI
11 references
retrieved
8 April 2019
stated in
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Network organization of the human autophagy system
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Towards a proteome-scale map of the human protein–protein interaction network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Construction and characterization of a normalized yeast two-hybrid library derived from a human protein-coding clone collection
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of bZIP interaction partners of viral proteins HBZ, MEQ, BZLF1, and K-bZIP using coiled-coil arrays
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
retrieved
8 April 2019
stated in
Pooled-matrix protein interaction screens using Barcode Fusion Genetics
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IEA
retrieved
8 April 2019
stated in
Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
The cAMP response element binding protein-2 (CREB-2) can interact with the C/EBP-homologous protein (CHOP)
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
biological process
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
determination method or standard
IDA
ISS
IGI
IEA
IMP
6 references
retrieved
8 April 2019
stated in
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
ISS
retrieved
8 April 2019
stated in
CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IMP
retrieved
8 April 2019
stated in
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IGI
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IEA
retrieved
8 April 2019
stated in
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
Q24299363
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
determination method or standard
IDA
TAS
IMP
IEA
6 references
retrieved
27 March 2018
stated in
Roles of CHOP/GADD153 in endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
TAS
retrieved
27 March 2018
stated in
The endoplasmic reticulum stress response in aging and age-related diseases
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
TAS
retrieved
27 March 2018
stated in
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
IMP
retrieved
27 March 2018
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
IEA
retrieved
27 March 2018
stated in
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
27 March 2018
stated in
Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?protein=P35638&geneProductId=UniProtKB:P35638
determination method or standard
IDA
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
determination method or standard
IBA
IDA
IEA
IMP
TAS
7 references
retrieved
8 April 2019
stated in
The endoplasmic reticulum stress response in aging and age-related diseases
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
TAS
retrieved
8 April 2019
stated in
Roles of CHOP/GADD153 in endoplasmic reticulum stress
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
TAS
retrieved
8 April 2019
stated in
CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IMP
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IEA
retrieved
8 April 2019
stated in
Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
C/EBP homology protein (CHOP) interacts with activating transcription factor 4 (ATF4) and negatively regulates the stress-dependent induction of the asparagine synthetase gene
GOA
curator
UniProt
UniProt protein ID
P35638
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P35638
determination method or standard
IBA

Identifiers

MeSH descriptor ID
D051742
subject named as
Transcription Factor CHOP
0 references
 
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